Sentences with phrase «bivalent epigenetic marks»
These bivalent epigenetic marks are thought to prepare their cognate loci for transcription, in a cell that is poised to embark on lineage commitment.
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The pluripotent population is characterized by a high degree of plasticity in chromatin structure [3], and lineage specific transcription factors show bivalent chromatin epigenetic marks characteristic of both suppression and inactivation [4].