Sentences with phrase «blast crisis»
The phrase "blast crisis" refers to a sudden and severe worsening of a serious medical condition, particularly in the context of a type of blood cancer called chronic myeloid leukemia. It signifies a rapid increase in immature and abnormal blood cells, which can lead to severe symptoms and complications. Full definition
In this study, Jamieson's team used human blast crisis chronic myeloid leukemia cells in the lab, and mice transplanted with these cells, to determine ADAR1's role in governing leukemia stem cells.
sciencedaily.com
Moreover, it inhibits DNA repair, causing genomic instability and potentially causing the feared blast crisis in CML.
Leukemia stem cells promote an aggressive, therapy - resistant form of the disease called blast crisis.
Self - renewal of blast crisis chronic myeloid leukemia cells was reduced by approximately 40 percent when treated with the small molecule, called 8 - Aza, as compared to untreated cells.
• Subject has BCR - ABL - positive leukemia (chronic myelogenous leukemia in blast crisis).
Although it did not eradicate CML cells, it did greatly limit the growth of the tumor clone and decreased the risk of the feared «blast crisis».