No one has yet shown success with SCNT using human tissue: The closest effort so far has been the cloned
blastocyst reported last year by workers at the Newcastle Fertility Centre in the U.K., but that did not yield ES cells.
Not exact matches
He was one of the first physicians to perform and
report on
blastocyst transfer in the United States.
In September a European team
reported coaxing human embryonic stem cells from an «arrested» IVF embryo — one that had stopped dividing before it reached the
blastocyst stage and thus died a natural death.
These genes were selected for analysis of parthenogenic and IVF / ICSI embryos at the morula and
blastocyst stage based primarily on published
reports from non-human model systems (Figure 3, 4A, 4B and Table S2).
Since the first
report of in vitro human oocyte maturation in 1969 [3], several
reports have documented
blastocyst (BL) development or live birth achieved from oocytes matured in vitro [1], [4], [5].
Interestingly, it has been
reported that mice with a mutation in Kap1 were obese and had behavioral problems, and the lower expression of Kap1 that we have found in the
blastocysts produced by IVC could also be related to the behavior problem
reported in mice generated by IVC [43].
In addition, genetic and epigenetic differences between males and females have been
reported at the preimplantation stage [19, 20, 36], indicating that at this early stage of development male and female
blastocysts can respond differently to IVC, affecting later development, and can differentially restore epigenetic marks between generations.