Visually, she is filming and analyzing time - lapse images of human embryos in the incubator and has been able to correlate various parameters of how cells divide with the probability that the embryos will make it to a full
blastocyst stage by day 5 - 6 of culture.
Not exact matches
They found that some sperm DNA methylation regions were also associated with poor
blastocyst stage of embryo quality as defined
by the IVF clinic's standards related to embryo quality before transfer into the uterus of the female partner to establish a pregnancy, Pilsner says.
The patent gives California - based Geron Corp. exclusive rights to animal embryos prepared
by transferring the nucleus of a quiescent diploid donor cell into a suitable recipient cell up to and including the
blastocyst stage.
The differentiation of the outer layer of
blastocyst cells from the inner cell mass is already underway
by the 8 - cell
stage.
OMC also aims at potentiating the existing Conditional Mutagenesis Facility
by implementing novel approaches to attain tissue -,
stage - and site - specific transgene expression in mouse mutant strains, mainly through lentiviral vector - mediated transduction of
blastocysts.
Changes in the manipulation medium, as well as a move from late to early
stages after first appearance of pronuclei, produced
blastocysts which were statistically indistinguishable from those produced in normal IVF
by measures of morphology, ploidy and gene expression.
The initial single cell combination is already dividing and
by the time of entry into the uterus, the egg might have already reached the
blastocyst stage.
Similarly, cytoplasmic maturation was also improved as indicated
by development to
blastocyst stage.
Then we tested functionality of oocytes matured in vitro
by assessing the ability to develop to the
blastocyst stage, and
by comparing the gene expression profiles of parthenogenic embryos and those obtained from IVF / ICSI.