Sentences with phrase «blastocysts generated»

The loss in ability to contribute to blastocysts generated in this transient PrEn - like state was interesting, but we wanted to establish if these cells had gained new properties.

Not exact matches

Although scientists have welcomed the development, they say the real breakthrough will be when someone manages to extract ES cells from the inner cell mass of cloned blastocysts and generate a cell line from them.

Just before implantation in the uterus, the ball of cells, called a blastocyst, gains the capacity to generate all of the cell types of the subsequent adult — a feature called pluripotency.

When the somatic cells are initially reprogrammed with the 4 genes and then allowed to divide, do they go to a blastocyst - like stage in which cells are taken to generate and perpetuate the iPS, or is it something different from that?

This was often done using blastocysts from IVF clinics that would otherwise be discarded (often because the blastocysts were damaged and would not properly develop into a human, although IVF generates a large number of excess healthy blastocysts that go unused as well).

Most strikingly when introduced back into morulae or blastocysts, the V+S + population is not effective at contributing to the epiblast and can contribute to the extra-embryonic visceral and parietal endoderm, while the V − S + population generates high contribution chimeras.

Interestingly, it has been reported that mice with a mutation in Kap1 were obese and had behavioral problems, and the lower expression of Kap1 that we have found in the blastocysts produced by IVC could also be related to the behavior problem reported in mice generated by IVC [43].