ES cell generation will include the isolation of the inner cell mass and subsequent growth of ES cells from
blastocysts obtained from five to ten superovulated females.
Parthenogenic blastocysts exhibited mRNA expression profiles similar to those of
blastocysts obtained after IVF / ICSI with the exception for MKLP2 and PEG1.
Not exact matches
Advanced Cell Technology, based in Santa Monica California, is developing embryonic stem cell therapies for macular degeneration and other conditions using cells
obtained non-destructively from an early embryo called a
blastocyst.
Twenty percent of the cells cloned in this way grew into early embryos, called
blastocysts, and 5 percent of them yielded embryonic stem cells, which is comparable with results
obtained from unfertilized eggs.
Then we tested functionality of oocytes matured in vitro by assessing the ability to develop to the
blastocyst stage, and by comparing the gene expression profiles of parthenogenic embryos and those
obtained from IVF / ICSI.