Sentences with phrase «blastocysts which»

Changes in the manipulation medium, as well as a move from late to early stages after first appearance of pronuclei, produced blastocysts which were statistically indistinguishable from those produced in normal IVF by measures of morphology, ploidy and gene expression.

The trophoblast is the outer layer of cells of the blastocyst which allow the fertilized ovum to attach to the uterus and which serves as a nutritive pathway for the embryo.

An embryo donated for research revealed two inner cell masses (ICMs, internal cluster of cells at the embryonic pole of the blastocyst which develops into the body of the embryo), which is a sign of monochorionic / diamniotic pregnancy that will give rise to MZ twins.

Not exact matches

Soon after conception, you may experience implantation bleeding, which occurs when the blastocyst attaches itself to the endometrial surface.

Our Virginia fertility center only performs embryo transfers five days after egg retrieval at the blastocyst stage, which results in a significantly higher rate than a Day 3 embryo transfer.

Embryos which progress to the blastocyst stage and are good quality can then be cryopreserved, if that is the couple's wishes.

This ball, called a blastocyst, has begun to produce the pregnancy hormone hCG, which tells your ovaries to stop releasing eggs.

It then stopped growing, far short of the 100 - cell blastocyst stage from which stem cells can be derived.

Because there are currently no precise methods for selecting viable embryos, couples typically choose to implant multiple blastocysts to enhance their chances of conceiving, which may also result in multiple pregnancies.

The most advanced embryo that we freeze is between 100 to 120 cells, which is known as a blastocyst.

Traditionally, the process involves plucking the inner cell mass from a 5 - day - old embryo known as a blastocyst (a round ball of 150 to 200 cells the size of a grain of sand), which destroys the embryo.

It is at this stage, when the fertilized egg is smaller than the period at the end of this sentence, that researchers extract the inner part of the blastocyst, from which embryonic stem cells are derived.

Twenty percent of the cells cloned in this way grew into early embryos, called blastocysts, and 5 percent of them yielded embryonic stem cells, which is comparable with results obtained from unfertilized eggs.

But researchers will have to figure out how to eliminate the viral DNA used to introduce the genes, which in Yamanaka's experiments led to cancers in 20 percent of mice grown from blastocysts.

Five days after fertilization, two distinct cell types are visible in the developing embryo, which is now called a blastocyst.

His group began with 242 eggs, but after removing the eggs» nuclei and swapping in those of somatic cells, the investigators produced only 30 blastocysts (week - old embryos), from which they coaxed just one stem cell line into being.

This accelerated early development meant that blastocysts from overweight and obese women contained fewer cells, most notably in the outermost layer, which goes on to form a large part of the placenta.

The smaller eggs from overweight and obese women were less likely to reach a crucial stage of development called the «blastocyst», which occurs around five days after fertilisation when the embryo resembles a hollow ball of cells.

The scientists also injected dye - tagged cells into blastocysts, which they inserted into female mice.

Embryonic development in mammals begins with the division of the fertilized egg, which is then followed by several further rounds of division to form the blastocyst, a sphere of cells made up of two layers of cells surrounding a fluid - filled cavity.

Figure 1: The blastocyst is a hollow sphere made of approximately 150 cells and contains three distinct areas: the trophoblast, which is the surrounding outer layer that contains the trophoblast stem cells and later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner cell mass, also known as the embryoblast, which can become the embryo proper, or fetus, and is where human embryonic stem cells are isolated from.

Though science has been trying to make human blastocysts, the embryonic stage at which stem cells can be harvested till now, the de-nucleated egg approach has not worked in humans.

Part of the normal variation, which is equally present between blastocysts of both groups, can be observed in the gene expression of levels mtDNA encoded OXPHOS proteins.

A few cell divisions later, the trophoblast contributes to significant cellular rearrangements in the embryo which make it enter the blastocyst stage (see Figure 1).

Also this technique is only likely to be useful in a small proportion of cycles in which embryos are cultured to the blastocyst stage and multiple embryos are then available for selection.

The blastocyst, which contains approximately 150 cells, is made up of three main parts: the blastocoel (an internal, fluid - filled cavity), the inner cell mass (ICM), and the trophoblast.

When the studies of mitochondrial carryover were done in embryonic stem cells derived from ePNT blastocysts (to allow for more cell divisions during which instability could manifest), some stem cell lines displayed instability and an increase in mitochondrial DNA carryover with time.

«The authors went on to study the resulting blastocysts for aneuploidy (frequency of abnormal chromosomes), and pattern of gene expression (which genes are active and at what level).

«The authors demonstrate that a number of technical manipulations improve the efficiency and outcome of the PNT procedure, which can be assessed by the quality of the blastocyst, the ball of cells resulting from the initial development of the zygote.

The blastocyst is a hollow sphere made of approximately 150 cells and contains three distinct areas: the trophoblast, which is the surrounding outer layer that later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner cell mass, also known as the embryoblast, which can become the embryo proper, or fetus, and is where hESCs are isolated from.

When the somatic cells are initially reprogrammed with the 4 genes and then allowed to divide, do they go to a blastocyst - like stage in which cells are taken to generate and perpetuate the iPS, or is it something different from that?

All embryos start from a fertilized egg, which, after completing its division process, leads to the formation of a blastocyst.

The embryos were allowed to grow for several days — to the blastocyst stage — at which point the researchers attempted to harvest stem cells from them.

Approximately ten to fifteen iPS cells were injected into the cavity of each blastocyst, all of which were kept in KSOM with amino acids until embryo transfer.

By activating a gene called Ras in cells bathed in a very specific culture medium, scientists were able to cause embryonic stem cells — which originate from the inner cell mass of the blastocyst — to become more like the trophoblastic stem cells that give rise to the placenta from the outer portion of the blastocyst.

The blastocyst, which becomes the embryo, forms after five days.

Taken together our data support a model in which ES cell culture has trapped a set of interconvertible cell states reminiscent of the early stages in blastocyst differentiation that may exist only transiently in the early embryo.

Referring to a scientific process within stem cell research that separates the fertilized egg prior to its cell generation, which occurs normally at 14 days old, he said, «I don't think we are baby killers when it comes to disaggregating the blastocyst.»

Embryonic stem cells derived from human blastocysts have the key advantage of pluripotency, meaning that they form nearly all cell types but also have the disadvantage of forming tumors in vivo, which may limit clinical application to tissue engineering rather than cell transplantation.

We have found that blastocysts produced by suboptimal IVC exhibit transcriptional repression of some genes (Sox2, Hdac1, Kap1, Dnmt1, and Dnmt3a) that are modifiers of epigenetic gene silencing through the regulation of the transcription of specific genes, which involves changes in the chromatin state.