Sentences with phrase «bleeding disorder known»

A bleeding disorder known as von Willebrand disease — known as a coagulopathy, this condition is associated with problems in how the blood clots.

Not exact matches

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

This is an important test, as we may not know your pet has this disorder until severe bleeding occurs during surgery or after a serious injury.

Epilepsy, joint problems, bleeding disorders, heart disease, eye diseases and endocrine system disorders are just some of the known problems in this breed.

FVIII deficiency, or Hemophilia A as it is more commonly known, is a clotting disorder which leads to excessive bleeding in affected animals.

Hip dysplasia, dermoid cysts, dwarfism, eye problems, von Willebrand's disease, cancer, bleeding disorders and gastric torsion, also known as bloat.

Von Willebrand's disease (vWD) was first recognized in humans, but is now known to be the most common inherited bleeding disorder in dogs.

The inherited blood - clotting disorder known as von Willebrand's disease results in excessive bleeding, and affected dogs might suffer frequent nosebleeds or gum bleeding.

But if you decline the bloodwork or if the clinic doesn't offer it, if your pet has an underlying medical issue (liver or kidney disease, bleeding disorder, etc.), the vet and staff will not know and the risk for surgical and post-op complications will go up.

I don't know why this dog died --- unknown or unintentional surgical complications, underlying metabolic disease, bleeding disorder, improper home care, etc. — but I do know that the owners had bred this dog, have had several of their dogs spayed at our clinic before without issue, they declined bloodwork, they didn't reveal pertinent medical history before surgery, and they didn't call or seek medical attention when they knew something wasn't right.