This pivotal trial is the largest
study conducted
of renal artery denervation as a treatment for resistant hypertension and the most rigorously designed, including
blinding and a sham treatment in the control
arm.
Methods: This
study is a two -
arm, parallel group, researcher -
blind, randomized controlled trial, to test the clinical effectiveness and cost - effectiveness
of a parenting intervention, Video Feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP - SD) for parents
of young children (12 — 36 months) at risk
of behavioural difficulties.