In a paper appearing online this week in the early edition of the journal Proceedings of the National Academy of Sciences, University of California, Berkeley, scientists who invented the photoswitch therapy and veterinary colleagues at the School of Veterinary Medicine of the University of Pennsylvania (UPenn) report that
blind mice regained the ability to navigate a water maze as well as normal mice.
A new genetic therapy not only helped
blind mice regain enough light sensitivity to distinguish flashing from non-flashing lights, but also restored light response to the retinas of dogs, setting the stage for future clinical trials of the therapy in humans.
Not exact matches
Just 6 hours after they were injected,
blind mice could learn to respond to light in the same way as sighted
mice — although Kramer says he doesn't know whether they
regained vision or just light sensitivity (Neuron, DOI: 10.1016 / j.neuron.2014.01.003).