Sentences with phrase «block gene transcription»

Not exact matches

It will block transcription during gene expression.

Based on previous work, the researchers had reason to think it was controlled by transcription factors — proteins that control the expression of certain genes by binding to DNA at specific locations to induce (or block) the transcription of information from DNA to RNA.

The therapy consists in injecting into the hippocampus - a region of the brain essential to memory processing - a gene which causes the production of a protein blocked in patients with Alzheimer's, the «Crtc1» (CREB regulated transcription coactivator - 1).

For example, in the case of the protein SIN3A, a regulator of gene transcription, the small molecule that covalently binds to its reactive lysine blocks the protein's function by disrupting SIN3A's interaction with another protein, TGIF1 — an interaction implicated in some invasive breast cancers.

Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the binding of NF - kB to DNA by blocking the transcription of different genes involved in both inflammatory and aging pathways (interlukin - 6, interlukin - 1 beta, tumor necrosis factor alpha) 27.

10/10/2007 Researchers Reveal Repressor Protein Blocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... MBlocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... Mblocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... More...

cassette upstream of a gene of interest blocks transcription when Cre is absent.

Partial block to transcription of human adenovirus type 2 late genes in abortively infected monkey cells