Sentences with phrase «block pancreatic tumor»

Liang Xu, Ph.D. member of the KU Cancer Center's Drug Discovery, Delivery and Experimental Therapeutics program and associate professor of molecular biosciences at KU, has discovered that targeting a cell - surface receptor called «CD44s» can block pancreatic tumor formation and recurrence after radiotherapy.

Not exact matches

With this information, the scientists tested the glucose - blocking anti-diabetes drug metformin, combined with the nanoparticle - encapsulated BPTES, on another eight mice implanted with human pancreatic tumors.

The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.

To validate their findings, the scientists injected the novel nanoparticles into pancreatic tumor - bearing mice and observed that by balancing these two targets — bringing them to a normal level by increasing their expression or blocking the gene responsible for their expression — they significantly prolonged the survival of the mice.

«Potential pancreatic cancer target challenged: New research finds PDX1 critical for cancer growth, but blocking it may lead to more aggressive tumors.»

People with pancreatic cancer may also itch — not from the cancer itself, but from a tumor blocking the bile duct.