Sentences with phrase «blocked endocannabinoid»
On the other hand, when they intentionally blocked their endocannabinoid system, the exercise wasn't followed by the same beneficial effects.
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He explained that rimonabant, a drug which blocked endocannabinoid signaling at cannabinoid receptors, was on the market in Europe for the treatment of human obesity.
Not exact matches
«Importantly, we found that blocking the actions of the endocannabinoids with pharmacological inhibitors of cannabinoid receptors in the periphery completely normalized food intake and meal patterns in western diet - induced obese mice to levels found in control lean mice fed standard chow.»
Numerous experiments with genetically altered mice and rats have shown that when natural brain compounds, called endocannabinoids, are missing or their receptors are blocked, the animals are more susceptible to pain, can not control their appetites, have trouble handling anxiety and are less able to cope with stress.
When an enzyme that normally breaks down 2 - AG was blocked, and the supply of the endocannabinoid was restored to normal levels, these behaviors were reversed, the researchers reported on Nov. 26 in the online edition of the journal Cell Reports.
However, when the researchers similarly blocked the animals» response to endorphins, while leaving their endocannabinoid system unchanged, the mice enjoyed all of the soothing effects of running.
But when the researchers used drugs to block the workings of some of the animals» endocannabinoid system, so that receptors in the animals» brains couldn't take up the molecules, their post-run cool disappeared.