Sentences with phrase «blocked ribosomes»

Sofar, studies have focused on how the RQC recognizes and clears blocked ribosomes in the cytosol.

This in turn blocks the ribosomes, the cell's protein factory.

Not exact matches

Ribosomes join up the building blocks of proteins in cells.

Noller (p. 1508) discusses how the basic building block of RNA — the double helix — has been fashioned into the intricate «protein - like» three - dimensional surfaces of the ribosome.

The collaboratinggroups at the MPIB and LMU have now investigated the clearance of ribosome - blocked proteins destined for the mitochondria.

The plasmid, which directs the production of the thiopeptide antibiotic, also directs production of a spare part for the ribosome, a replacement for the part that is blocked by the antibiotic, which renders the ribosome insensitive to the antibiotic.

The resistance gene, however, by changing the shape of the ribosome, succeeds in blocking the drug — but at the cost of slowing down protein output.

Instead, the signal peptide adopts a specific conformation in the presence of the antibiotic, which blocks and inhibits the active center of the ribosome, thus accounting for the premature stop.

The three - letter «words» indicate which amino acid — the building blocks of proteins — the ribosome should add next to its growing chain of peptides.

Walter isolated the six building blocks of the apparatus and dubbed it the signal recognition particle; by the early 1980s, he had demonstrated that the apparatus recruits ribosomes to the ER, latches onto address tags on proteins minted on ribosomes, and transfers proteins to the interior of the ER.