Sentences with phrase «blocking inflammatory cytokines»

It works by blocking inflammatory cytokines and enzymes.

Statin drugs block the inflammatory cytokine release in the post operative patient, thus reducing mortality from the procedure.

Not exact matches

Administration of inflammatory cytokines to otherwise non-depressed individuals causes symptoms of depression, whereas the blocking of cytokines has been shown to reduce depressive symptoms.

All 10 patients who received the CTL119 cells experienced mild cytokine release syndrome (CRS), a known potentially lethal type of toxicity, within a few days after receiving their infusions; however, none required treatment with tocilizumab, an immunosuppressant drug that blocks the effects of the inflammatory cytokine IL - 6.

The research suggests that a cytokine produced by inflammatory cells near a prostate tumor induces cancer cells to decrease production of a protein that blocks metastasis.

«If we can block the interaction of this cytokine with its receptor, we may be able to inhibit all of this cascade that we have defined and potentially develop a therapeutic for patients with inflammatory bowel disease, particularly ulcerative colitis,» Denning said.

Nine patients were treated with tocilizumab, an immunosuppressant drug that blocks the effects of the inflammatory cytokine IL - 6, which have been found to spike during the most robust phase of the engineered cells» expansion in the body.

All six had cytokine release syndrome (CRS), from which they recovered after treatment with tocilizumab, an immunosuppressant drug that blocks the effects of the inflammatory cytokine IL - 6.

They show that highly purified NS1 acts as a pathogen - associated molecular pattern (PAMP) that activates mouse macrophages and human peripheral blood mononuclear cells (PBMCs) in culture via TLR4, resulting in release of inflammatory cytokines — an effect that was blocked by either a TLR4 antagonist or an anti-TLR4 antibody.

In another experiment, blocking the activity of inflammatory cytokines in the presence of DENV NS1 did not prevent disruption of human cell layers similar to those found in the lining of blood vessels.

In addition, the hippocampus of T2DM - AD - Vehicle mice showed increased proinflammatory cytokines IL - 1β and TNF - α and gliosis, and rivastigmine treatment blocked these inflammatory reactions.

Vitamin D plays a strong role in modulating the inflammatory immune response by blocking pro-inflammatory cytokines such as interleukin 10.