Not exact matches
Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and
Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when
blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in
cell and rodent models of type 1 and 2 diabetes, chemotherapy - induced neuropathy and HIV.
Researchers led by Van Allen and Choueiri sought an explanation for why some patients with a form of metastatic
kidney cancer called clear
cell renal
cell cancer (ccRCC) gain clinical benefit — sometimes durable — from treatment with immune checkpoint inhibitors that
block the PD - 1 checkpoint, while other patients don't.
Two clinical trials that used antibodies to
block PD - 1 and PD - L1, a related molecule that binds to PD - 1, resulted in significant and long lasting responses against melanoma skin cancer, renal
cell (
kidney) cancer, and lung cancer.
Dog's urine normally contains a trace amount of protein in the urine, as proteins are
blocked by the glomerulus, the part of the
kidney that filters waste products, or pass through the glomerulus and then reabsorbed by renal tubes or broken down by the epithelial
cells of the renal tubes.