Sentences with phrase «blocking myostatin»

In addition, researchers at the American Diabetes and Obesity Center of Excellence found that blocking myostatin raises the body's sensitivity to leptin, the satiety hormone, which helps curb hunger more efficiently in terms of a reduced - calorie diet.
To determine whether the FLRG transgene was causing increased muscle growth by blocking myostatin activity, I examined the effect of combining the FLRG transgene with a loss - of - function mutation in the myostatin gene.
The drug, which is currently in clinical trials, blocks myostatin — and perhaps GDF11 as well.
Of course, there is a lot more research needed for this to be anywhere close to relevant to our normal daily lives, but this experiment proves that it is indeed possible to create a quick drug that would block our myostatin production and allow us to mimic the effects of exercise on our bodies, even when we're not moving off the couch.

Not exact matches

I have presented data showing that FLRG, like follistatin, can promote muscle growth when expressed as a transgene in skeletal muscle and that both of these molecules appear to act by blocking not only myostatin but also other ligands with similar activity to myostatin.
Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin / activin - blocked mdx mice.
It is the flip - side of myostatin, as increased follistatin blocks the activity of myostatin: either increased follistatin or reduced myostatin produce similar outcomes in animal studies, with treated individuals demonstrating increased muscle mass.
Of course, we've known about myostatin for a while now, and we knew that if we somehow succeeded in blocking it, we could have amazing muscle gains with reduced gym time, as well as significantly reduced risk of heart or kidney illnesses.
Researchers found that when myostatin was absent in animals, or its action was blocked, the animals displayed massive increases in muscle mass, and decreases in fat mass [1 - 9].
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