Treatments include hormonal contraceptives, sometimes combined with spironolactone, which
blocks androgen production or its effects on hair follicles.
Not exact matches
Hormone therapy is used for treatment of prostate cancer to
block the
production of
androgens, or male sex hormones.
Denmeade says the combination of drugs that
block testosterone
production and receptors, called
androgen deprivation therapy, may make prostate cancer more aggressive over time by enabling prostate cancer cells to subvert attempts to
block testosterone receptors.
These patients were subsequently treated with the drug ketoconazole, which
blocks the
production of
androgens outside of the testes (e.g., those developed by prostate cancer cells that are evading ADT treatment).
Abiraterone works by
blocking CYP17A1, an enzyme that is crucial for the
production of
androgens.
«We have demonstrated for the first time that Hsp90 inhibitors can
block the
production of the most common abnormal
androgen receptors that cause many prostate cancers to stop responding to current treatments.
The new research found that on top of their known effects on cancer, Hsp90 inhibition also
blocked production of abnormal forms of the
androgen receptor, stripping cancer cells of their defences against hormone treatments.
One treatment is temporary chemical castration, using birth control pills,
androgens (male hormones),
androgen blockers, synthetic estrogens, Lupron or similar drugs that
block hormone
production.