Flutamide
blocks androgen receptors on hair follicle cells so androgens can't connect to the receptors.
When Barton and colleagues
blocked androgen receptor in these cells, the cells died.
Androgens, like testosterone, encourage the growth of prostate cancer cells, so scientists designed drugs called selective androgen receptor antagonists / modulators (SARMs) to
block androgen receptors.
One user said his «libido and sexual function generally declined» and apparently milk thistle can
both block androgen receptors (study) and raise prolactin, which has anti-testosterone effects.
Not exact matches
Denmeade says the combination of drugs that
block testosterone production and
receptors, called
androgen deprivation therapy, may make prostate cancer more aggressive over time by enabling prostate cancer cells to subvert attempts to
block testosterone
receptors.
Such a drug would
block only the
androgen receptor in prostate cells, and so stop the chain of reactions leading to further tumour growth, says McCague.
«We have demonstrated for the first time that Hsp90 inhibitors can
block the production of the most common abnormal
androgen receptors that cause many prostate cancers to stop responding to current treatments.
The new research found that on top of their known effects on cancer, Hsp90 inhibition also
blocked production of abnormal forms of the
androgen receptor, stripping cancer cells of their defences against hormone treatments.
Vinclozolin
blocks cell
receptors that are normally activated by the hormone
androgen.
Apalutamide binds to the
androgen receptor,
blocking its activation by testosterone and other
androgens.
In addition, not only are some of them estrogen mimickers, but others will suppress your enzymatic activity necessary to produce
androgen hormones, while other will
block the
receptor sites on the cell.
«We think some women may get more vulvar dryness with birth control pills because the pills are
blocking male sex hormones called
androgens, and the vulva has
androgen receptors.»