Sentences with phrase «blocks axonal»

When it is experimentally prevented (either by severing the projecting axons, by treating them with the drug vinblastine, which blocks axonal transport, or by administering 6 - hydroxydopamine, which destroys the nerve endings), the innervating sympathetic neurons in the ganglion die off.
The lethal effects of blocking the axonal transport of NGF can be completely overcome, however, by supplying the cell bodies with externally administered NGF.

Not exact matches

Inhibiting this channel blocked the formation of axonal varicosities.
In the current study, Freeman and colleagues identified Axed, showed that it functions downstream of SARM to execute axonal degeneration, and, surprisingly, that the protection afforded by blocking Axed was even stronger than SARM.
We hypothesize that these aggregating proteins also block the transport of normally transported axonal proteins, and thus cause neurodegeneration and neuronal death by impairing axonal transport.
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