Sentences with phrase «blocks hyaluronan»

A better understanding of the factors contributing to these anomalies may contribute to the development of new treatments for these common birth defects, such as hymecromone, a drug approved in many parts of the world that blocks hyaluronan synthesis.

Not exact matches

We identified a specific bioactive hyaluronan fragment (bHAf) that downregulates myelin gene expression and chronically blocks OPC maturation and myelination via a tolerance - like mechanism that dysregulates pro-myelination signaling via AKT.

Glycosaminoglycans such as hyaluronan and proteoglycan components such as heparan sulfate and chondroitin sulfate are important building blocks of the extracellular matrix.