Sentences with phrase «blood cell changes»

Blood tests can show white blood cell changes, which occur with parasites, allergies, and infections.

These red blood cell changes can be subtle but important diagnostic clues in an otherwise normal CBC.

Persian cats and young kittens are felt to be sensitive to its side effects, which usually are limited to nausea but can include liver disease and serious white blood cell changes.

Cats infected with the Feline Immunodeficiency Virus commonly develop life - threatening blood cell changes and should never be exposed to this medication.

Then there's the many studies on animals; one dermal study conducted on rabbits found that chlorpropham «produced skin irritation and blood cell changes.»

«Malaria parasite causes red blood cell changes, study suggests.»

It occurs when some of the red blood cells change into a «sickle» shape and cause a buildup of red blood cells in small blood vessels.

Not exact matches

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During intense or extensive exertion, the sickle hemoglobin can change the shape of red blood cells from round to quarter - moon, or «sickle.»

Keep in mind that if your baby has been ill recently, his iron levels may be temporarily low due to the illness (see Hoffman, Ronald, et al. «Chapter 154: Hematologic Manifestations of Childhood Illness: Infectious Disease Changes in Red Blood Cells: Anemia of Acute Infections.»

The composition of your blood also changes, creating a higher ratio of plasma to red blood cells than in non-pregnant women.

Some of these changes happen in the final weeks of pregnancy, including the stage when red blood cell production is transferred from the liver to the bone marrow.

Following combined exposure to the two substances, the leukemia cells underwent substantial changes and, to the surprise of the researchers, started to turn back into normal blood cells.

The researchers attribute this decrease to the way that microgravity changes the interaction between blood vessel capillaries and red blood cells, but say that more research is needed to understand what is happening in the capillaries.

It also sought to match epigenetic changes and genetic differences to the physical characteristics of each cell type and use this knowledge to understand how these can lead to blood disorders, cancer and other complex diseases.

«Landmark project shows heart disease, rheumatoid arthritis risk raised by genetic changes in blood cells.»

«A surprise was how many major changes occurred to genes in the blood cells,» Yang said.

The project's goals were to explore and describe the range of epigenetic changes that take place in bone marrow as stem cells develop into different types of mature blood cell.

His group assessed the animals for changes in body weight as well as potential toxicity to the liver, kidney, and blood cells — none of which was observed.

As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the change in pressure from the flowing liquid is the cue for cells lining the aorta to change first into blood stem cells, then into all blood - cell types in the body.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

This showed leukocytes crossing between the blood - nerve barrier endothelial cells without gaps in the barrier or change in how the barrier is structured.

By analyzing chemical changes of the IRS - 2 protein in immortalized cultures of human white blood cells, it determined that IRS - 2 appeared in two different forms — «on,» which allows the signal to pass through, and «off,» which stops the signal from activating the cells into M2 macrophages.

Results suggest that while isotretinoin was associated with a change in the average value of some laboratory tests (white blood cell count and hepatic and lipid panels), the average change across a patient group did not meet the criteria for high - risk and the proportion of patients with laboratory abnormalities was low, the authors report.

How sleep apnea is related to these conditions is debated, but Cavadas and her co-authors propose that prolonged disruptions in blood oxygen levels and sleep fragmentation can generate stem cell exhaustion, epigenetic changes, increased inflammation, and other hallmarks of aging.

And his group has applied for funding to run lab studies to see if the fish hosting blotchy lesions develop more subtle — and disturbing — symptoms with time, such as a slower swimming speed or changes in blood - cell counts.

Although many scientists doubt that Orlic's bone - marrow stem cells actually morphed directly into new heart tissue, they do believe the cells may have secreted powerful chemical cues — growth factors — or perhaps changed into blood vessels that revitalized the hearts.

Stem cells are immature blood cells and, in theory, introducing the gene into them should produce a permanent change in that individual's maturing blood cells.

The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).

Keeping blood for prolonged periods of time leads to a series of biochemical and biomechanical changes in red blood cells called storage lesions.

Stem cells from umbilical cord blood are highly prized for their ability to change into the cells of other tissues.

Aware that cancers rewire their metabolism in ways that could change the epigenome and that distant metastases in pancreatic cancer naturally spread to organs fed by a sugar - rich blood supply, the researchers wondered if the tumor cells had altered the way they use the basic form of sugar, glucose.

The bile acids accumulate in the blood and interact with the TGR5 receptor on white fat cells to change their metabolic function.

Blood cells stored for transfusion also change shape as they age.

In sickle cell disease, individuals have two copies of a genetic mutation that produces an abnormal change in hemoglobin, the primary molecule that carries oxygen in the blood.

This change can lead to severe anemia and abnormally shaped red blood cells that can block the flow of blood, causing organ damage.

Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem cells embark on their journey from quiescent reserve cells to multi-lineage progenitor cells, which form the many highly specialized cell types that circulate within the blood stream.

The American Red Cross and the researchers themselves were quick to say the study is not definitive enough to change the current practice of matching red blood cell donors to recipients.

However, when chronic inflammation occurs in a blood vessel — typically in response to diabetes, high cholesterol and cigarette smoking — the smooth muscle cells in the walls of arteries change their behavior.

The most recent finding: Even short exposures to high elevation can unleash a complex cascade of changes within red blood cells that make it easier for them to cope with low - oxygen conditions.

In adults, more cannabinoids will force one group of cells to more intensive work, but at the same time it will weaken the efficiency of the other, and in consequence blood glucose level will not change or may even increase significantly.»

The changes included a marked decline in antiviral responses that correlated with clearance of virus from white blood cells.

Andrabi therefore analyzed how B cells in the VRC26 lineage changed in CAP256's blood in the course of HIV infection.

Aging is a key risk factor for sAML because, over time, hematopoietic stem cells (which give rise to all other blood cell types) accumulate DNA mutations and changes in other molecules that put DNA instructions into action, such as RNA and proteins.

The team found significant changes in gene expression after light exposure in all cell types in the visual cortex — both neurons and, unexpectedly, nonneuronal cells such as astrocytes, macrophages and muscle cells that line blood vessels in the brain.

A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.

Jamieson's team wanted to understand how RNA might change with the aging of normal blood stem cells compared with sAML stem cells.

With this type of cancer, the genes in the white blood cells affected change slightly, causing two chromosomes to cross.

«The use of whole genome sequencing and the sheer number of samples we collected gave us a detailed picture of how the var gene repertoire changes continuously within red blood cells.»

When two copies of the altered hemoglobin gene are present, they cause the shape of the hemoglobin to change so much that the «sickled» blood cells don't flow freely in the blood vessels, causing excruciating pain.