Sentences with phrase «blood cell enzyme»

Pyruvate kinase deficiency: a deficiency of a specific red blood cell enzyme.

Phosphofructokinase deficiency: a deficiency of a specific red blood cell enzyme in English springer spaniels.

Not exact matches

The white blood cells produce an enzyme that destroys the surface of the follicle allowing the bacteria to enter the skin layer causing inflammation of the skin.

(HELLP syndrome: A syndrome featuring a combination of «H» for hemolysis — breakage of red blood cells, «EL» for elevated liver enzymes, and «LP» for low platelet count — an essential blood clotting element.)

The liver has started producing the various enzymes that are necessary to break down bilirubin, which is the result of red blood cells breaking down inside your baby.

The name is an acronym for hemolysis, the breakdown of red blood cells; elevated liver enzymes; and low platelets, the blood cells that are necessary for clotting.

HELLP syndrome is named for its primary symptoms: Hemolysis (H), or the breakdown of red blood cells, elevated liver enzymes (EL), and low platelet count (LP) occurring in pregnancy.

For instance, breast milk contains antibodies, enzymes, and white blood cells that boost the immune system and help protect a baby against infections.

It is the breaking down of red blood cells, elevated liver enzymes and low platelet count (scary!).

Usually, the G6PD enzyme in the body PROTECTS the red blood cells from damage by these byproducts... but when an individual is G6PD deficient, that layer of protection is not there in sufficient quantity.

G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose -6-phosphate dehydrogenase, or G6PD, which helps red blood cells (RBCs) function normally.

HELLP — which stands for hemolysis (the destruction of red blood cells), elevated liver enzymes and low platelet count — syndrome is a more severe form of preeclampsia, and can rapidly become life - threatening for both you and your baby.

Mature milk is comprised mostly of fat, water, carbohydrates, vitamins, protein, minerals, enzymes, amino acids and white blood cells.

Newborns become jaundiced in the first few days because the enzyme in the liver maybe immature and does a process of breaking down these red blood cells as rapidly.

The enzyme at the center of this study, ADAR1, is normally expressed during fetal development to help blood cells form.

Lu's team will extract immune cells called T cells from the blood of the enrolled patients, and then use CRISPR — Cas9 technology — which pairs a molecular guide able to identify specific genetic sequences on a chromosome with an enzyme that can snip the chromosome at that spot — to knock out a gene in the cells.

The enzyme is produced by white blood cells called neutrophils, which play an important role in inflammatory and immune responses and may be a key contributor to the development of muscular dystrophy.

1984 - 1986: In 1984, Randall Willis and collaborators partially cured Lesch - Nyhan disease — an enzyme deficiency that causes neurological problems and self - mutilation behavior — in human cells, and in 1986, Philip Kantoff and colleagues corrected another enzyme deficiency in human blood cells.

First author Kim Martinod, a graduate student in the Immunology Graduate Program at the Harvard University Medical School, found that, in response to vein constriction, these «rescued» mice now could function normally, forming clots as efficiently as mice with a functioning Pad4 gene, demonstrating that the Pad4 gene did produce a functioning PAD4 enzyme in these white blood cells to regulate blood clotting.

Insulin is an enzyme that helps transport sugars from the blood into cells for use as fuel.

Red blood cell catechol - O - methyltransferase, histamine - N - methyltransferase, and a methanol - forming enzyme were examined in a number of subjects with mental diseases.

Known as Abl, it is one of a family of enzymes that usually help guide normal cell growth, but a mutation of it drives white blood cells to divide incessantly.

A similar enzyme is impaired in ALD, leading to high blood levels of very long chain fatty acids (VLCFAs) in patients and — for reasons poorly understood — progressive degeneration of brain cells.

«Enzyme discovered that keeps blood stem cells functional to prevent anemia.»

The microbe swims freely through the blood and feeds off its host, behaving like the single - celled animal it is, but it produces enzymes and lipids thought to be exclusive to plants.

Myeloperoxidase is an enzyme in leukocytes (white blood cells) that is effective in killing various microorganisms.

They have now discovered that the protein is released by damaged cells and is then truncated by enzymes secreted by mastocytes, white blood cells that are key factors in allergy.

This enzyme usually dispatches a toxic molecule from white blood cells.

The researchers removed immune cells from the recipient's blood and then disabled a gene in them using CRISPR — Cas9, which combines a DNA - cutting enzyme with a molecular guide that can be programmed to tell the enzyme precisely where to cut.

The cell biologist helped explain how blood clots form by identifying factor XIII, the enzyme that binds proteins together to create a plug in a wound, preventing a person from bleeding to death.

«Blood cancers develop when immune cell DNA editing hits off - target spots: Team urges consideration of cutting - and - pasting errors when using enzymes for gene modification.»

In mice, when white blood cells in the lungs engulf spores of a common airborne fungus, these immune cells release an enzyme that sends the fungal cells into programmed cell death.

«Body's own gene editing system generates leukemia stem cells: Inhibiting the editing enzyme may provide a new therapeutic approach for blood cancers.»

They found that there was no measurable difference between the concentrations of stem cells in the various samples, despite the fact that the in vivo sample was part of a dynamic environment — which included enzymes and blood flow — making it easier for the stem cells to migrate away from the target site.

The findings, published Feb. 10 in the journal Cancer Cell, raise hopes that treatment strategies that focus on both enzymes simultaneously could help bring molecularly targeted treatments to AML, a common blood cancer.

For this purpose, they use certain enzymes, proteases that break down the tissue surrounding the tumor, thus opening the way for tumor cells to reach blood or lymphatic vessels.

The trial participants had T cells removed from their blood and then modified in the laboratory with a designer enzyme engineered by Sangamo BioSciences in Richmond, California.

There is a caveat, however: The enzyme Hunter patients now receive does not cross the blood - brain barrier, the tight network of cells that protects the brain from pathogens, and the livermade enzyme produced by the gene edit may not either.

An enzyme known as SHP - 1, which can suppress the growth of smooth muscle cells lining the inside of blood vessels, plays a crucial role in stent failure, says George King, M.D., Joslin's Chief Scientific Officer and senior author on a paper in the journal Diabetologia describing the work.

Other genetic diseases include Tay - Sachs disease (damage to the gene for the enzyme hexosaminidase A leads to an accumulation of a chemical in the brain that destroys it), sickle cell anemia (improper coding of the gene that produces hemoglobin), hemophilia (lack of a gene for a blood - clotting factor) and muscular dystrophy (caused by a defective gene on the X chromosome).

You can give enzymes in the blood, but it won't cross the blood brain barrier; but if you give cells, or a transplant, then it will engraft in the brain as well and produce enzyme, or the other factors that are missing.

Enzymatic crosslinking is the way in which our blood clots during wound healing — cells secrete an enzyme, transglutaminase, which crosslinks fibrin, forming an insoluble protein polymer, or clot.

Three leukemias that affect as many as 100,000 people in the United States are all caused by acquired mutations that alter a specific enzyme controlling blood cell proliferation, according to new...

Using standard enzyme - linked immunosorbent assays (ELISA) and peripheral blood mononuclear cell (PBMC) assays, researchers discovered that unlike previously described human antibodies to lipids, WR321 did not react with any of 17 other lipids it was tested against, including cholesterol, glycolipids, and other phospholipids such as cardiolipin and phosphatidylserine, but it bound specifically only to two phosphoinositides.

METHODS: Peripheral blood mononuclear cells obtained from patients who received AN1792 were stimulated in vitro either with beta - amyloid (Abeta) or various overlapping peptides of Abeta (1 - 42), followed by quantification of cytokine - secreting cells by enzyme - linked immunosorbent spot assay.

Additionally, the blood cells have less of the enzyme IFI16 that detects viral DNA fragments in the cell.

Glucose -6-Phosphate Dehydrogenase (G6PD) Deficiency: G6PD is an important element (enzyme) in the glucose oxidation (oxygen utilization) process of red blood cells and for maintaining their normal life span.

For some time now, scientists have been looking at using enzymes derived from bacteria to «clip» the A - or B - specific sugars (aka antigens) off of red blood cells, to create a sort of generic blood that can be given to anyone.

Using an enzyme to remove sugars from red blood cells, it may be possible to give type A, B or AB blood to anybody (Photo: Shutterstock)

Though monoclonal antibodies were a model product in his 18 years CMO experience, process development was also performed for enzymes, hormones, blood factors, immuno - modulants and vaccines with different expression systems such as hybridoma, myeloma, CHO, BHK, insect - cell / baculovirus, adherent animal and human cells.