Sentences with phrase «blood cell lineages»

Then, they transplanted these cells into recipient mice and confirmed that the cells can form all of the blood cell lineages in vivo.

In effect, this is gene therapy, since the donor's genes are replacing the patients genes in the blood cell lineages.

First, the trial tested GM - CSFs which act on more than one blood cell lineage and are not commonly used nowadays.

Not exact matches

Andrabi therefore analyzed how B cells in the VRC26 lineage changed in CAP256's blood in the course of HIV infection.

Blood founder cells showed a much lower propensity for aberrant methylation than did other founder cells, which could explain why in the past scientists attributed the founder cell to the effectiveness of differentiating iPS cells to the hematopoietic lineage.

«We get almost all lineages of blood cells that you would expect from bone marrow.»

«Irreversible resolution of lineage priming appears to be a common feature of blood cell differentiation and may in fact be a general feature of other developmental processes.»

BLOOD VESSEL VS. HEART LINEAGES Researcher: Bertie Göttgens, Principle Investigator, Cambridge Stem Cell Institute, U.K. Project: Göttgens and his collaborators are working to solve a long - standing question in developmental biology: To what extent do blood vessel and heart lineages overlap, and when do they divBLOOD VESSEL VS. HEART LINEAGES Researcher: Bertie Göttgens, Principle Investigator, Cambridge Stem Cell Institute, U.K. Project: Göttgens and his collaborators are working to solve a long - standing question in developmental biology: To what extent do blood vessel and heart lineages overlap, and when do they LINEAGES Researcher: Bertie Göttgens, Principle Investigator, Cambridge Stem Cell Institute, U.K. Project: Göttgens and his collaborators are working to solve a long - standing question in developmental biology: To what extent do blood vessel and heart lineages overlap, and when do they divblood vessel and heart lineages overlap, and when do they lineages overlap, and when do they diverge?

The decision whether the cells differentiate into the blood - or vessel - lineage seems to correlate with the expression of certain «master switch genes».

Data from two external large scale datasets was added to cells of the blood lineage.

The researchers hypothesize that in older people, many of the cell lineages in the blood have reached their maximum number of cell divisions and died off, leaving the ones that have divided more slowly and, therefore, have accumulated fewer mutations.

We use the Haplobank in reverse genetic screens to investigate the temporal resolution of essential genes in mES cells, and to identify novel genes that control sprouting angiogenesis and lineage specification of blood vessels.

Here, we used a marker - free approach to computationally reconstruct the blood lineage tree in zebrafish and order cells along their differentiation trajectory, based on their global transcriptional differences.

We used the mutations to reconstruct developmental lineages of adult cells and demonstrate that the two daughter cells of many early embryonic cell - doubling events contribute asymmetrically to adult blood at an approximately 2:1 ratio.

Utilizing sophisticated genetically engineered mouse models, we will study how these conserved longevity pathways regulate the homeostasis and aging of adult stem cells, including hematopoietic stem cells, the adult stem cells that sustain all blood lineages throughout life.

Since then, researchers have expanded this line of investigation to document that the tumor cells can differentiate along various lineages, including myeloid (white blood cells), adipose (fat cells), and vascular (blood vessel forming cells).