Sentences with phrase «blood cells block»

VOC occurs when the misshapen, sickled red blood cells block blood flow in the blood vessels.

Figure B shows abnormal, sickled red blood cells blocking blood flow in a blood vessel.

Not exact matches

Cord blood includes potent stem cells, which are considered to be the building blocks of the body.

They found that antibiotics disrupted the mice's gut microbiomes, decreasing the activity of neutrophils and blocking these important white blood cells from responding when needed.

This protein overload leads to unbalanced stem cell growth and dramatically blocks differentiation to blood cells.

The researchers confirmed this hypothesis by showing that if they blocked YAP1 they could inhibit stem cells from undergoing self - renewal, forming blood vessel - like structures, and reduce lung cancer cell growth in mice.

This drug (vedolizumab) blocks a specific adhesion molecule on the surface of the T - cell and thereby inhibits immune cells from binding themselves to receptors present in the intestine, preventing the T - cells from penetrating the blood vessels in the intestinal tissue.

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

Patients received a tandem of lenalidomide, a drug that kills tumor cells, blocks blood vessel growth, and acts on the immune system, and dexamethasone, an anti-inflammatory agent, plus one of three new agents:

Imatinib is an inhibitor that blocks the ATP - binding site of the tyrosine kinase Abl in affected blood cells, thereby suppressing their overactivity.

Scientists from Singapore's Nanyang Technological University (NTU) have discovered a key process during the invasion of the blood cell by the Malaria parasite, and more importantly, found a way to block this invasion.

Hence, if one red blood cell door is blocked, the parasite finds another way to enter,» said senior author Manoj Duraisingh, John LaPorte Given Professor of Immunology and Infectious Diseases at Harvard Chan.

This blood vessel normalization results in an increased barrier function on the one hand — thereby blocking cancer cell dissemination and metastasis - and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

Medicines used to treat diabetes fall into four groups: those that stimulate the pancreas to put out more insulin; those that lower insulin resistance in cells; those that help the body use insulin; and those that slow down or block the breakdown of starches, which in turn keeps blood - glucose levels lower.

In experiments in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two weeks.

This change can lead to severe anemia and abnormally shaped red blood cells that can block the flow of blood, causing organ damage.

He and colleagues figured that if the p53 protein was responsible for the positive switch, then blocking it in mice would halt the transition from scar - forming cells to blood vessel - forming cells.

The experimental drug cediranib blocks the cell surface receptor VEGF, which stimulates the growth of new blood vessels to feed the growth of tumours,» explains study researcher Dr Paul Symonds, of the Department Cancer Studies & Molecular Medicine at the University of Leicester, UK.

Clusters of infected cells form clots, blocking the flow of blood.

An injection of SLex into the bloodstream should block the E-selectin on the surface of the blood vessels and so hide the chemical message that alerts the white blood cells.

Antibodies can therefore protect at two levels: in the initial phase, by blocking sporozoites, and in the acute phase of the disease, by blocking the infected red blood cells.

Then, in some fatal cases, the fungal filaments began to grow in the brain, attracting platelets and white and red blood cells to aggregate around the filaments and form a mass that could block a blood vessel and initiate a stroke.

CD47 is key to protecting red blood cells from macrophages, and red blood cells are particularly sensitive to the blocking effects of the antibody as they get older, Leeper says.

If this could be made easily, it could be injected to block E-selectin and so control white blood cells.

Kurtis says a vaccine that exploits the antibody's ability to imprison Plasmodium within blood cells would have more time to work with than one that tries to block reinfection.

They show that highly purified NS1 acts as a pathogen - associated molecular pattern (PAMP) that activates mouse macrophages and human peripheral blood mononuclear cells (PBMCs) in culture via TLR4, resulting in release of inflammatory cytokines — an effect that was blocked by either a TLR4 antagonist or an anti-TLR4 antibody.

Specifically, they were able to determine that Wars2 plays an important role in supplying sufficient endothelial cells, the building blocks of blood vessels, for angiogenesis.

Peter Carmeliet and his team demonstrated that endothelial cells can be paralyzed by blocking glycolysis and consequently stop to form blood vessels.

«Many researchers are trying to find ways to develop a malaria vaccine by preventing the parasite from entering the red blood cell, and here we found a way to block it from leaving the cell once it has entered.

The surface of a red blood cell is dotted with complement receptors, proteins that block complement from entering the cell and attacking it.

Researchers believe blocking the pore leaves the parasite fatally imprisoned, unable to steal resources from the red blood cell or dispose of its wastes.

In another experiment, blocking the activity of inflammatory cytokines in the presence of DENV NS1 did not prevent disruption of human cell layers similar to those found in the lining of blood vessels.

They learned that the protein blocks the malaria parasite from leaving the blood cells it manages to infect.

Watching what cells do inside the bone is tricky: Blood - producing stem cells are rare, and bones block many of the tools that scientists would use to spy on the cells.

We came across a compound that had been isolated from a plant species and shown to have effects on blocking the growth of blood vessel cells, both in the culture dish and also in animal models.

This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.

Furthermore, saturated fat has been shown to have numerous positive effects on health, such as improving liver health by encouraging the liver cells to get rid of their fat cells, improving the immune system's response by helping white blood cells to recognize and destroy invaders more effectively, enabling the absorption of fat - soluble vitamins by acting as their carriers, as well as improving hormonal activity by providing the building blocks for a variety of hormones that are essential to human health.

Stroke What it is: Most strokes occur when a blood clot blocks an artery or a blood vessel, interrupting blood flow to an area of the brain over a period of minutes or hours, causing brain cells to die.

The second contains just one drug, Amevive (alefacept), which works by blocking the white blood cells known as T cells.

1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth

Fluoride also blocks the migration of white blood cells to the site of infection in the body, damaging the immune system's ability to destroy pathogens.

The RT3 was blocking my cell receptors and keeping me hypo as the T3 pooled in my blood, barely keeping me alive.

Results from previous studies have demonstrated that blocking just one of the steps can significantly reduce neutrophil recruitment... When there is a site of inflammation in the body, the blood flow increases because the blood transports immune cells to the site to promote healing.

Other problem areas include: phytates, which block the body's uptake of minerals; enzyme inhibitors, which hinder protein digestion; and haemagglutinin, which causes red blood cells to clump together and inhibits oxygen take - up and growth.

They end up blocking circulation, damage heart action, inhibit cell renewal and impede the free flow of blood (and thus oxygen) and lymph fluids.

This nutrient also provides the building blocks for immune cells, blood cells, enzymes and hormones.

High blood glucose causes acne through increased sebum production, formation of blood free radicals called AGEs, and an increase in dead skin cell turnover which blocks your pores.

Foods like kale, beets, and brussel sprouts are loaded with iron, a building block for the red blood cells that transport oxygen around the body (which means it's essential for energy).

Those abnormal cells tend to be sticky and can block blood flow — causing symptoms such pain, fatigue and shortness of breath.

Blood cells can collect with worms, literally clogging arteries and blocking the valves of the heart.