Sentences with phrase «blood cells in a laboratory»

October 17, 1994 Boost for bone marrow transplants By growing billions of infection - fighting white blood cells in the laboratory, University of Chicago researchers hope to reduce the 14 - day period when patients are at greatest risk to as little three days.

Not exact matches

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

Using these cells, the team modeled the patients» neurons and blood - brain barrier in a laboratory dish.

Results suggest that while isotretinoin was associated with a change in the average value of some laboratory tests (white blood cell count and hepatic and lipid panels), the average change across a patient group did not meet the criteria for high - risk and the proportion of patients with laboratory abnormalities was low, the authors report.

«Despite the low infection levels of mouse cells with oHSV, we were able to cause a delay in tumor growth in one of the cancer models and even cure many of the mice in a second model,» said first author Jennifer Leddon, who conducted much of the laboratory work during a research experience in the Center for Childhood Cancer and Blood Diseases.

Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.

While blood cells live in a convenient, easily studied liquid, most other cell types have been harder to analyze in the laboratory.

Schiffman and his team conducted another series of experiments in the laboratory on blood samples from adult African elephants to find how these genes respond to DNA damage in the elephant cells.

«Notably, we also observed a small increase in blood histamine levels and a slight release of tryptase from mast cells in the skin of unaffected individuals exposed to vibration,» said Hirsh Komarow, M.D., of NIAID's Laboratory of Allergic Diseases, the senior author of the study.

Aifantis, the chair of the Department of Pathology at NYU Langone and a member of its Perlmutter Cancer Center, and an early career scientist at the Howard Hughes Medical Institute, says experiments in his laboratory had shown that leukemia - initiating cells concentrate in the bone marrow near CXCL12 - producing blood vessels.

A team from Cold Spring Harbor Laboratory in Long Island, N.Y., reports that it staved off full - blown metastasis in mice by preventing mini-tumors in the lungs from recruiting stem cells called endothelial progenitors, which assemble into blood vessels to nourish the malignancy.

Gene editing techniques have the potential to treat blood disorders that run in families, such as thalassemia and sickle cell anemia, but their application has been largely limited to cells in a laboratory and not living animals.

Bone marrow cells and newborn babies» umbilical cords are being considered as sources for laboratory blood, but those are limited in quantity and useful only to the donor, while hESCs could prove to be an unlimited source of universally transfusable blood.

These tiny objects (1 / 4th of the size a red blood cell) are first created inside a computer using simulations and then fabricated in the laboratory.

In the study, USC Stem Cell researcher Casey Brewer and colleagues in the laboratory of Rong Lu found that transplantation dose affects the behavior of blood - forming stem cells in bone marrow — called hematopoietic stem cells, or HSCIn the study, USC Stem Cell researcher Casey Brewer and colleagues in the laboratory of Rong Lu found that transplantation dose affects the behavior of blood - forming stem cells in bone marrow — called hematopoietic stem cells, or HSCin the laboratory of Rong Lu found that transplantation dose affects the behavior of blood - forming stem cells in bone marrow — called hematopoietic stem cells, or HSCin bone marrow — called hematopoietic stem cells, or HSCs.

For the study, conducted as part of the doctoral thesis of Mahesh Raundhal, a graduate student in the laboratory of Prabir Ray, Ph.D., Pitt professor of medicine and co-senior author, the research team examined lung cell samples obtained from patients also participating in the Severe Asthma Research Program (SARP), a National Heart, Lung, and Blood Institute of the National Institutes of Health - sponsored program to improve the understanding of severe asthma.

The university recently received international attention after a group of 16 scientists based at the Key Laboratory of Gene Engineering published the results of a controversial experiment in which they genetically modified single - cell human embryos to repair the human β - globin (HBB) gene in a procedure aimed at preventing a serious blood disorder (www.sciencemag.org/content/348/6234/486.full).

I was supporting myself with night - shift laboratory work analysing immune cells in blood samples flown in by helicopter, often arriving after midnight... nothing related to my thesis.

A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life - threatening high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report in the May issue of the journal Experimental Hematology.

The treatment involves collected blood stem cells carrying the genetic anomaly of patients and corrected them in the laboratory by introducing a healthy WAS gene using a lentiviral vector developed and produced by Genethon.

«Our laboratory is specialized in deciphering the molecular mechanisms involved in the recruitment of white blood cells, explains Dr. Adama Sidibé, a researcher at the Faculty of Medicine at UNIGE and the first author of this work.

Whilst the gene needs to be studied in greater depth to understand its potential for use in the clinic, we show that targeting KAT2A destroyed AML cells in the laboratory while sparing healthy blood cells.»

The trial participants had T cells removed from their blood and then modified in the laboratory with a designer enzyme engineered by Sangamo BioSciences in Richmond, California.

To solve that problem, the researchers started with patients» blood cells and reprogrammed them into so - called induced pluripotent stem cells, which can make any other cell in the body and grow indefinitely in the laboratory.

Dr. Robert A.J. Signer, a postdoctoral research fellow in Dr. Morrison's laboratory and first author of the study, realized that this reagent could be adapted to measure new protein synthesis by stem cells and other cells in the blood - forming system.

Ralph Steinman and Nina Bhardwaj, independently with other laboratories, discover the plasmacytoid dendritic cell (pDC) subset in circulating blood.

In laboratory experiments, malignant white blood cells and primary cells from autoimmune disease patients have been shown to be much more sensitive to Leukothera than their normal counterparts.

In laboratory experiments, Dr. Weinberger and his team inserted a green fluorescent protein, or «vector,» into the DNA of Jurkat T lymphocytes — a type of white blood cell that helps maintain a healthy human immune system.

Right now, in our laboratories, our scientists are looking for ways to create insulin - producing cells in the laboratory, engineer blood vessels for heart bypass surgery and apply our regenerative medicine technologies to battlefield injuries through co-leading a $ 85 million federal grant, as well as many other novel research initiatives.

For the other adult patients that might still benefit from a cord blood donor, either two cord blood units are combined for a single transplant, or more recently, there are some exciting new graft engineering technologies that are emerging to expand stem or progenitor cells in the laboratory before infusion or modify the cells in some way to make them more potent at the time of transplant.

Reported in eLife, the findings from researchers from the Wellcome Sanger Institute in Cambridge and the European Molecular Biology Laboratory in Rome could aid research into creating new blood cells for transplants and for understanding cancer metastasis.

In the new study, however, the researchers used blood samples of monkeys with Zika virus and Zika - infected laboratory cells.

Since 1997, he has directed the investigation of neurodegenerative diseases in the Nurses» Health Study and other large cohorts comprising more than 400,000 men and women who have provided detailed information on their dietary habits and lifestyle in addition to blood or cheek cell samples for genetic and other laboratory analyses.

In a study using human muscle tissue, scientists in Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cellIn a study using human muscle tissue, scientists in Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cellin Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage ceCell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cecell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cellin the laboratory into muscle, bone and cartilage cells.

Prior to joining Spectrum Health, he was chief of the Division of Hematologic Malignancies and Blood and Marrow Transplantation and director of the stem cell laboratory at Roger Williams Medical Center in Providence, Rhode Island, an academic affiliate of Boston University School of Medicine.

The laboratory has a strong interest in developmental stem cell biology with a focus on understanding the development of the liver and blood - forming tissues.

Her laboratory focuses on the roles of the actin cytoskeleton in cell architecture and physiology in organs such as muscle, blood and eyes.

In other major projects in the laboratory, we investigate the molecular mechanisms that regulate endothelial cell polarization and movement, a critical and initiating event in the formation of new blood vessels and in repair of injured vesselIn other major projects in the laboratory, we investigate the molecular mechanisms that regulate endothelial cell polarization and movement, a critical and initiating event in the formation of new blood vessels and in repair of injured vesselin the laboratory, we investigate the molecular mechanisms that regulate endothelial cell polarization and movement, a critical and initiating event in the formation of new blood vessels and in repair of injured vesselin the formation of new blood vessels and in repair of injured vesselin repair of injured vessels.

SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.

And while the human and T cells they studied in the laboratory were not specifically skin T cells they were isolated from mouse cell culture and from human blood — the skin has a large share of T cells in humans, he says, approximately twice the number circulating in the blood.

The study concludes that infectious virions constitute only a small fraction of a typical HIV - 1 preparation and that, in a laboratory setting, all of the infectious virions can bind to red blood cells and other non-permissive cells (i.e., cells that can not be infected).

Among it's valuable components are gamma - linolenic acid (GLA), linoleic and arachidonic acids, vitamin B12 (needed, especially for vegetarians, for healthy red blood cells), iron, a high level of protein (60 to 70 percent), essential amino acids, the nucleic acids RNA and DNA, chlorophyll, and phycocyanin, a blue pigment that is found only in blue - green algae and that has increased the survival rate of mice with liver cancer in laboratory experiments.

This lag in energy production tends to occur earlier than changes in blood cell production, so the muscle fatigue and changes in concentration are likely to be noticeable long before laboratory testing shows low blood cell production.

In - house laboratory tests include: standard blood chemistries, red and white blood cell counts, parvo virus, heartworm infection, giardia, feline leukemia and feline immunodeficiency virus.

In patients with normal kidney function, oliguria can indicate dehydration, and the small amount of urine produced will likely be concentrated (urine specific gravity [USG] > 1.030).5 Other laboratory parameters that change with dehydration include packed cell volume and total protein (PCV / TP) levels, which demonstrate hemoconcentration (high PCV) and hyperproteinemia (high TP) in dehydrated patients5 due to the loss of the fluid portion of the blood as the body tries to maintain fluid balance and homeostasiIn patients with normal kidney function, oliguria can indicate dehydration, and the small amount of urine produced will likely be concentrated (urine specific gravity [USG] > 1.030).5 Other laboratory parameters that change with dehydration include packed cell volume and total protein (PCV / TP) levels, which demonstrate hemoconcentration (high PCV) and hyperproteinemia (high TP) in dehydrated patients5 due to the loss of the fluid portion of the blood as the body tries to maintain fluid balance and homeostasiin dehydrated patients5 due to the loss of the fluid portion of the blood as the body tries to maintain fluid balance and homeostasis.

The laboratory can count the number of red blood cells; there are millions in a drop of blood.

Laboratory: Our in - house laboratory equipment allows for extremely rapid evaluations of your pet's organ function (white blood cell counts, chemistries, elecLaboratory: Our in - house laboratory equipment allows for extremely rapid evaluations of your pet's organ function (white blood cell counts, chemistries, eleclaboratory equipment allows for extremely rapid evaluations of your pet's organ function (white blood cell counts, chemistries, electrolytes).

After irradiating the tumor, veterinarians collect a particular type of the dog's white blood cells, known as Natural Killer (NK) cells, then stimulate and grow the cells in a laboratory before injecting them back into the dog's tumor.

Laboratory: Our in - house laboratory facilities provide for evaluation of white and red blood cell counts, electrolytes, blood chemistries including liver, kidney and pancreatic values, infectious disease screening for lyme, giardia, ehrlichia, anaplasma, heartworm diseases, as well as FLaboratory: Our in - house laboratory facilities provide for evaluation of white and red blood cell counts, electrolytes, blood chemistries including liver, kidney and pancreatic values, infectious disease screening for lyme, giardia, ehrlichia, anaplasma, heartworm diseases, as well as Flaboratory facilities provide for evaluation of white and red blood cell counts, electrolytes, blood chemistries including liver, kidney and pancreatic values, infectious disease screening for lyme, giardia, ehrlichia, anaplasma, heartworm diseases, as well as FIV / FeLV.

Re-directed Autologous T cell Therapy for drug resistant or refractory CD20 + B cell lymphoma Overview: In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-..In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-..in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-...]