Researchers would now like to know if Klotho levels in humans correlate with life span — for example, if
the blood of centenarians is swimming with it.
Not exact matches
Genetic screening later revealed that 24 percent
of centenarians from Ashkenazi Jewish populations carry a variant in the CETP gene — an enzyme important for cholesterol metabolism — that reduces the level
of the protein CETP in the
blood and is linked to a lower prevalence
of hypertension, cardiovascular disease and memory loss.
Lower than typical
blood glucose is found in almost all models
of extended lifespan (and healthspan) including caloric restriction and
centenarians.
However, there are 3 consistent
blood metabolic indicators
of all
centenarians which are relatively consistent: low sugar, low triglycerides, and low insulin.