Of 68 people taking the drug in the trial, over 90 percent had
blood phosphate levels reach and stay in the normal range after 24 weeks of treatment, Ultragenyx announced in April.
When dietary restriction alone is not sufficient to control the
elevated blood phosphate levels, aluminum hydroxide is used to reduce the amount of phosphorus absorbed from the intestines.
Many human enema preparations (eg fleet enemas) contain phosphate, and, as I mentioned before, anything that makes your pet's
blood phosphate level rise above normal will make its blood calcium level drop.
We add phosphate binders if we find
their blood phosphate levels are creeping up.
Once your pet is stable, your veterinarian will monitor
the blood phosphate levels at 4 - 6 week intervals to ensure that the dose remains correct and that your pet still requires the medication.
Your veterinarian will begin treatment of your pet with a dose of aluminum hydroxide that is determined by the degree of elevation of
the blood phosphate levels.