They identified more than 559 lipids that were significantly different (q < 0.05) between control and patient samples, of which 55 were structurally identified by matching to entries in
a blood plasma lipid AMT tag database.
Not exact matches
Using samples from the Dominantly Inherited Alzheimer Network (DIAN) study, the researchers found that people who carried the mutation responsible for this form of Alzheimer's also had altered levels of specific
lipids in their
blood plasma compared to the control group.
Researchers at the University of Chicago have found an unsuspected link between the immune system and high
plasma lipid levels (cholesterol and triglycerides in the
blood) in mice.
We delve into very fundamental problems such as «how does a malaria red
blood cell attach itself to a
blood vessel» or «how does binding of a ligand to a cell surface receptor or contact of a crystalline surface with the
plasma membrane drive
lipid sorting and how will this lead to signalling» but then immediately apply it to a practical problem such as «how does contact of uric acid crystals with dendritic cells cause gout in affected joints and how can we prevent this occurrence?»
The metabolic analysis of the mice could be combined with clinical assessments, by performing biochemical analysis in
blood,
plasma, urine and tissues (i.e,
lipid and cholesterol content, glycogen content...) and by performing autopsy of the animal at the end of phenotyping study with several tissue collections (i.e, histology, mRNA anlaysis, protein analysis...).
Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter
plasma concentrations of C - reactive protein, interleukin - 6, tumor necrosis factor alpha, and adiponectin; and did not significantly affect other risk factors for coronary heart disease (
blood pressure and
plasma glucose, insulin, and
lipid concentrations) in either group.
The
blood glucose,
plasma insulin, hemoglobin, glycated hemoglobin, activities of the various antioxidant enzymes (catalase, superoxide dismutase, glutathione peroxidase and glutathione reductase) and
lipid peroxidation markers (malondialdehyde, hydroperoxides and conjugated dienes) were evaluated in all the groups.
Fasting
blood samples were processed on the same day for serum
lipids,
plasma glucose concentrations, white
blood cell (WBC) count, and fibrinogen by the Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, Australia.
Albumin normally constitutes about 60 % of human
plasma protein and plays an important role in regulating
blood volume by maintaining the oncoosmotic pressure of
blood needed to avoid edema, and by serving as the carrier for hydrophobic molecules, including
lipid soluble hormones, bile salts, unconjugated bilirubin, free fatty acids (apoprotein), calcium, ions (transferrin), and some drugs (e.g., warfarin, phenobutazone, clofibrate & phenytoin).
«there were no significant difference between the dietary groups for other outcome measures such as serum
lipids,
blood pressure and fasting
plasma glucose»
There are also other features of the metabolic syndrome that are influenced by different types of fat, particularly
blood pressure and
plasma lipid levels.
Vitamins C (ascorbic acid) and E (gamma - tocopherol), along with several polyphenols, have been shown to reduce the amount of platelets and
plasma lipids in the
blood and decrease
blood pressure, which reduces the risk of serious heart disease.
Effect of oral zinc supplementation upon
plasma lipids,
blood pressure, and other variables, in young adult white males.