Sentences with phrase «blood stem cell»

This treatment is called peripheral blood stem cell transplantation.
We see from human medicine that peripheral blood stem cell transplantation, in conjunction with chemotherapy, has raised human survival rates considerably.»
Patients were randomly assigned to receive either peripheral blood stem cell or to bone marrow transplantation, based partially on their disease risk and transplantation center.
Moffitt has a stem cell transplant program, and most of the institutions administering CAR T - cell therapy have robust hematopoietic blood stem cell transplant programs because many of the steps involved in CAR T - cell therapy resemble a stem cell transplant, so those pieces are already in place.
City of Hope is one of the world's largest and most successful bone marrow and blood stem cell transplant centers.
What are hematopoietic cell transplantation (HCT) and peripheral blood stem cell transplantation (PBSCT)?
The researchers say the special «plasticity» of the blood stem cell that allows them to be transformed to a heart cell, holds important clues about how leukemia and other blood diseases develop and how they can be controlled.
A blood stem cell transplant is a medical procedure for people with a variety of life - threatening diseases.
National Cancer Institute: Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation
Scientists have long viewed in utero blood stem cell transplantation as a promising treatment strategy for many genetic diseases diagnosed as early as the first trimester of pregnancy, including sickle cell disease and certain immune disorders.
«Enhanced cord blood stem cell transplants safe in long - term studies.»
We published the first experience with double autologous peripheral blood stem cell transplant for high - risk neuroblastoma.
Although cord blood stem cell transplant is becoming increasingly promising, the Clinical Islet Program is not currently involved with cord blood as a treatment for diabetes.
Blood stem cell cultures: Blood stem cells from colonies (cell clusters) in vitro consisting of different blood cells.
Nine blood stem cell colonies are illustrated in the image, which have developed into differentiated cell types, particularly into white blood cells (leukocytes).
Several clinics outside the U.S. also offer cord blood stem cell treatments for autism.
In a 2015 report, they said that although the approach had no impact on acute GVHD in 35 patients who received peripheral blood stem cell transplants, it sharply reduced the risk of the disease's chronic form.
Wartman has a chronic form of graft - versus - host disease (GVHD), a debilitating consequence of blood stem cell transplants.
To find out if this was true, workers in stem - cell biologist Irving Weissman's lab at Stanford University Medical School took one blood stem cell from an adult mouse and tagged it with a marker that glowed green under fluorescent light.
He began to show immediate improvement and after three cycles of treatment received a blood stem cell transplant, and since has been cancer free for 19 months.
«Blood stem cell self - renewal dependent on surroundings: Blood formation: Bone marrow, blood stem cells work in close harmony.»
Systems biologist Prof. Thomas Höfer and colleagues (also of the DKFZ) performed mathematical analysis of these experimental data to provide additional insight into blood stem cell dynamics.
Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.
We even saw where his cord blood stem cells would be stored!»
This means that they will take the umbilical cord blood stem cells and store them for future use in medical emergencies.
Your baby's cord blood stem cells have amazing healing potential.
Still, scientists are hopeful that someday adult patients will routinely be able to receive cell therapies based on cord blood stem cells.
Cord blood stem cells are also often a better option for medical treatments than bone marrow, another option often used in stem cell therapies.
Cord blood stem cells can be used to treat dozens of diseases and are being tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.
In leukemia cells it is often the case that genes are reactivated that, in physiological terms, mediate the self - renewal of blood stem cells.
They are particularly responsible for the self - renewal of blood stem cells.
«Mechanism vital to keeping blood stem cells functional uncovered.»
As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the change in pressure from the flowing liquid is the cue for cells lining the aorta to change first into blood stem cells, then into all blood - cell types in the body.
«Every blood and immune cell in our body descends from blood stem cells,» he said.
This fits with studies we've conducted in the past in which we found that the gene primes blood stem cells for leukaemic transformation.»
He says the structure could also offer a new way of studying blood stem cells and how blood disorders arise.
Blood stem cells are found in bone marrow and produce all blood cells in the body.
Scientists are a step closer to creating blood stem cells that could reduce the need for bone marrow transplants in patients with cancer or blood disorders.
«leukemia results from the gradual accumulation of DNA mutations in blood stem cells, in a process that can take decades,» explains Dr Thomas McKerrell, joint first author from the Wellcome Trust Sanger Institute.
«Blood stem cells study could pave the way for new cancer therapy.»
It plans to use Crispr for engineering immune cells and blood stem cells, and as a research tool for drug discovery.
Shane Mayack was a postdoc in the lab of Amy Wagers at Harvard University's Joslin Diabetes Center, studying blood stem cells.
In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.
«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.
This method would also enable them to follow potential aging processes that occur in blood stem cells in detail as they occur naturally in a living organism.
Dr. Katrin Busch from Rodewald's team developed genetically modified mice by introducing a protein into their blood stem cells that sends out a yellow fluorescent signal.
Scientists from the German Cancer Research Center (DKFZ) have developed a way to equip mouse blood stem cells with a fluorescent marker that can be switched on from the outside.
Blood stem cells in the bone marrow have been labeled with a fluorescent marker protein.
In the United States, Mackenzie's group and another have embraced a different approach: treating fetuses with blood stem cells culled from their mothers, the strategy she began exploring in animals almost a decade ago.
In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via progenitor cells at various stages of maturation.
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