Not exact matches
While it's important to make sure it isn't
blood, the «brick colored» stain of
urate crystals is a very common cause of this frightening finding in newborns.
Primarily supported by a $ 5.6 million grant from the The Michael J. Fox Foundation for Parkinson's Research and conducted at 17 sites across the U.S., SURE - PD (Safety of
URate Elevation in Parkinson's Disease) enrolled 75 recently diagnosed Parkinson disease patients with relatively low
blood levels of
urate (less than 6 mg / dL).
The tested dosages successfully increased
blood and cerebrospinal fluid
urate levels into the target ranges, with greater increases in the moderate - elevation group.
Studies by Schwarzschild's team and others have found that healthy people with naturally occurring
blood levels of
urate within the high normal range appear to have a reduced risk of developing Parkinson's and that the disease may progress more slowly in those with higher
urate levels.
«This study provided clear evidence that, in people with early Parkinson disease, inosine treatment can safely elevate
urate levels in the
blood and cerebrospinal fluid for months or years,» says Michael Schwarzschild, MD, PhD, principal investigator of the study and an MGH neurologist.
Blood tests measured the
urate level of participants.
«High levels of
urate in
blood associated with lower risk of Parkinson's disease.»
Gout is a common inflammatory arthritis caused by
urate crystal formation resulting from a high concentration of uric acid in the
blood, which is in turn caused by an imbalance in the dietary intake of purines and in the synthesis an excretion of
urate.
If the
blood is collected from a toenail, the nail must be scrupulously cleaned so that no excreted
urates contaminate the sample.