When the breast is emptied,
the body signals the cells that make milk to begin making more.
Not exact matches
Immunotherapy differs from more traditional cancer treatments, such as surgery (cutting malignant
cells out of the
body), chemotherapy and radiation (poisoning the deadly mutants), and even the newer, more precise molecular drugs that attempt to jam the protein
signals that tell tumor
cells to keep dividing and conquering.
With virtual anatomy, there's nothing in the
body we can't see: a heart beating, nerves
signaling in the brain, a
cell dividing, an infection raging.
The human
body has about 1,000 kinds of such receptors, structures on the surface of
cells, which let the
body respond to a wide variety of chemical
signals, like adrenaline.
Protein is hugely important for our
body - it aids in muscle repair, speeds up chemical reactions and plays a role in
cell signalling.
Improved understanding of the biology of cancer
cells has led to the development of biological agents that mimic some of the natural
signals that the
body uses to regulate growth.
Mitochondria, specialized organelles found in nearly every
cell of the
body, use cellular respiration to generate one of the most important sources of chemical energy — adenosine triphosphate (ATP), a versatile nucleotide that powers everything from
cell division to
cell signaling to transportation of large molecules across the
cell membrane.
When tumor
cells are present in an environment that lacks oxygen and nutrients, they receive a
signal that it is time for the
cells to move to a different part of the
body.
A
signal from the virus tells the liver
cells to manufacture the growth promoter, which is then secreted back into the bloodstream and ferried off to muscles throughout the
body.
Further study revealed that these so - called immune proteins are actually present on the surface of certain nerve
cells, but that they functioned differently in the brain than they did in the rest of the
body; rather than scouting for germs, they influenced
signals sent between neurons.
In another neuron called a chandelier
cell (above), vertical branches of its
signal - sending axon, which serves to quiet other
cells, dangle around the
cell body.
Signals from the dendritic
cells prime them to trigger immune reactions in other parts of the
body.
Was there a chemical or genetic
signal that induced stem
cells to create the complex structures of the
body and brain?
The human
body is a complex electrical network: Nerve
cells shuttle
signals from the brain, and pulses in the heart cause its muscle
cells to expand and contract.
It was already known that cold temperatures stimulate brown fat, but was unclear how the
body signals that message to its
cells.
Inside your
cells, proteins allow your
body to break down food to power your muscles, send
signals through your brain that control the
body, and transport nutrients through your blood.
Osteocalcin also
signals fat
cells to release a hormone that increases the
body's sensitivity to insulin, the
body's blood sugar moderator, Karsenty and colleagues reported in
Cell in 2007.
«Something similar occurs in our
bodies when we're infected with these viruses; there are
signals our
cells detect that let our immune system know all is not well,» he said.
About ten years ago, research results showed that things are not quite as simple as that: «Under most conditions, H2O2 is not an undesired side product but rather an essential chemical messenger that plays an important role in regulating the way in which
body cells respond to
signals from outside such as hormones and growth factors,» says Dr. Tobias Dick of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).
Special heart
cells create electrical
signals that cause the heart's upper and lower chambers to beat in the proper sequence to pump blood through the
body.
To unravel the complex journey of the
body's GPCRs, scientists used biophysical tools, including fluorescent biosensors; biochemical tools, such as
cell signaling in neuronal cultures; as well as computational models.
All volunteers experienced similar flu - like symptoms, increased
body temperature and white blood
cell count, and higher concentrations of inflammatory and
signaling proteins, demonstrating to investigators that lexaptepid did not interfere with the immune response process.
It is comprised of lipid
signaling molecules called endocannabinoids — which can be thought of as the
body's own «natural cannabis» — that bind to cannabinoid receptors located on
cells throughout the
body.
Once engineered
cells are engrafted into laboratory mice, their GRN becomes even closer to that of the true target tissue, indicating that the
body's own tissues contribute
signals to enhance the performance of transplanted
cells.
Leptin, which is made by fat
cells, is thought to
signal the
body that it has enough energy in reserve to launch into the growth spurt and other changes of puberty.
We would know the basic structure of every last one of its proteins: every enzyme in its metabolism, every
signal - bearing hormone coursing through its
body, every receptor poised to receive those
signals on the surface of its
cells.
When the
body encounters an infection, a molecular
signaling system ramps up the
body's infection - fighting system to produce more white blood
cells to attack invading bacteria.
In addition to suppressing the mature blood
cells battling against the infection, malfunctioning of this
signaling system results in permanent damage to the
body's blood producing
cells — called hematopoietic stem
cells — that are located in the bone marrow.
In another test, the researchers looked to see if chemical
signals released from the endothelial
cells would cause the media layer to relax and constrict, as they do in the human
body.
The normal function of RIPK2 is to send warning
signals to
cells that bacterial infection has occurred, which in turn spurs the
body to mobilize white blood
cells.
One theory is the DHA helps
cells send an anti-inflammatory
signal to the
body so it doesn't overcompensate and trigger an autoimmune response.
When a virus invades a
cell, one of the
body's first
signals that it's under attack comes from type I interferon proteins, which then rev up the production of hundreds of proteins that fight the virus.
Previous research conducted by Dr. Badylak's team suggested that ECM also could be used to regenerate lost muscle by placing the material in the injury site where it
signals the
body to recruit stem and other progenitor
cells to rebuild healthy tissue.
Jagged1 plays a key role in a
cell signaling pathway involved in many
body systems, but it was not previously known to affect Duchenne muscular dystrophy.
Mammals are known to fend off viruses with a system based on interferons,
signaling proteins made by immune
cells that amplify the
body's attack on invaders.
Overriding the
body's defenses by suppressing the
signaling between key immune
cells, plague races through the lymphatic system, invading organs such as the spleen, the lungs, and especially the liver.
Pain Amplifier A pain
signal is just your
body's way of alerting you to damage in your
cells.
Axons, the long projections of neural
cells which form the nerves of our peripheral nervous system, are like electrical cables: they have thick electrical insulation so that they can quickly relay stimuli from the
body and
signals from the brain to a toe, for example.
For example, the
body's
cells can recognize «
signaling imbalances» in their own internal circuitry that might cause them to proliferate wildly, causing cancer.
Normally, when the
body detects an outside invader such as a virus, a
signalling system known as the PKA pathway responds by turning on 99 genes that then activate T -
cells to destroy the invader.
Studies in animals suggest that mesenchymal stem
cells play important roles in the
body's ability to heal after an injury, although researchers are still working out the
signals and steps required to steer their differentiation into one type of tissue or another.
Infected
cells in a
body send out a
signal that attracts immune
cells.
«This debris left by dead
cells can mistakenly
signal to the
body that there is an infection that warrants immune action, triggering the innate immune system,» said Bruce A. Sullenger, Ph.D., director of the Duke Translational Research Institute.
The team at Barts Cancer Institute, part of Queen Mary University of London, have found that a molecule, called focal adhesion kinase (FAK),
signals the
body to repair itself after chemotherapy or radiotherapy, which kill cancer
cells by damaging DNA.
These
cells are on high alert for pathogens such as viruses, bacteria and even tumor
cells,
signaling the
body's T -
cell immune fighters into action when sensing harmful invaders.
They then added
signalling molecules to make the stem
cells develop into motor neurons, the
cells that carry
signals to and from the spinal cord to the rest of the
body.
The federally funded study, published in the Journal of Leukocyte Biology, showed how a stress receptor, known as corticotropin - releasing factor, or CRF1, can send
signals to certain immune
cells, called mast
cells, and control how they defend the
body.
They cultivated human muscle
cells and artificially synchronised them in the absence of a master clock, using a
signal molecule normally secreted in the
body.
«It's likely that these microbial
signals reach other
cells throughout the
body, which in turn mount their own specific responses,» Rawls said.
Moreover, these stem
cell - derived
cells released different amounts of hormone in response to known feedback
signals generated by other organs in the
body.