Sentences with phrase «bone and cartilage destruction»

Rheumatoid arthritis (RA) is a disease mainly defined by its clinical features of chronic inflammation in joints associated with bone and cartilage destruction.

Not exact matches

The therapies, hotly pursued by pharmaceutical companies, inhibit proteins called kinases, and aim to halt the inflammation that causes debilitating pain and eventual destruction of bone and cartilage.
Histopathology in Tg197 mice is characterized by infiltration of inflammatory cells, synovial hyperplasia, articular cartilage destruction and bone erosion symptoms, closely resembling those of human rheumatoid arthritis.
Figure 2: Representative histology images of A: wild type and B: Tg197 animals at 7 weeks of age depicting the symptoms of Infiltration of inflammatory cells, Synovial hyperplasia, Articular cartilage destruction and Bone erosions evident as Tg5453 arthritic pathology.
Arthritis: Joints of TNFΔARE mice display severe pathological features of chronic symmetrical inflammatory polyarthritis, including hyperplasia of the synovial membrane, presence of inflammatory infiltrate, bone erosion and articular cartilage destruction.
CHD is a developmental disease of the bones in which the head of the thigh bone poorly fits the hip socket, causing damage to the cartilage, gradual destruction of the joint, pain and swelling.
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