Sentences with phrase «bone cell precursors»
By carefully guiding the cells» choices at each fork in the road, Loh and Chen were able to generate bone cell precursors that formed human bone when transplanted into laboratory mice and beating heart muscle cells, as well as 10 other mesodermal - derived cell lineages.
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The reset cells, known as induced pluripotent stem cells (iPS cells), gave rise to healthy precursors of bone marrow stem cells (Nature, DOI: 10.1038 / nature08129).
One company, Melbourne, Australia — based Mesoblast, is already in late - stage clinical trials, treating hundreds of chronic heart failure patients with stem cell precursors drawn from healthy donors» hip bones.
In 1868, however, the German pathologist Ernst Neumann discovered immature precursor cells in bone marrow, which turned out to be the actual site of blood cell formation, also known as hematopoiesis.
In recent experiments, precursors of bone and connective tissue cells regenerated on the scaffold, yielding the desired properties for tendon reattachment.
When the researchers performed a similar experiment with precursors of bone building cells, the precursors boosted their production of RANK ligand, the group reports in the February Journal of Clinical Investigation.
In 2014, the FDA approved Amgen's BLINCYTO ® (blinatumumab), the first BiTE ® therapy to receive FDA approval, for the treatment of Philadelphia chromosome - negative relapsed or refractory B - cell precursor acute lymphoblastic leukemia, a rare and rapidly progressing cancer of the blood and bone marrow.
Effects of the chemokine stromal cell - derived factor - 1 on the migration and localization of precursor - B acute lymphoblastic leukemia cells within bone marrow stromal layers.
All immune cells come from «precursor» cells or stem cells, located in the bone marrow.
We now show that astrocytes generated from the same population of human fetal glial precursor cells, by exposure to either bone morphogenetic protein (BMP) or ciliary neurotrophic factor (CNTF), promote widely divergent outcomes with respect to repairing the injured adult spinal cord.
His group defined a functional niche for B cells (around sinusoids in the bone marrow), identified the first two mutants that abrogate marginal zone B lymphocyte development, developed the concept of a follicular versus marginal zone B lymphoid cell - fate decision, and discovered two new defined stages of peripheral B cell development, the marginal zone precursor (MZP) B cell, and the Follicular type II B cell.
Angelica Sinensis Angelica has been shown to stimulate the proliferation of precursor cells to maintain bone health.
It's called Panleukopenia because of how the virus will temporarily wipe out the infected cat or kitten's bone marrow of the precursor cells that produce white blood cells, red blood cells, and platelets.