Sentences with phrase «bone defects»

Scientists report today the generation of patient - specific bone substitutes from skin cells for repair of large bone defects.

Leaving food down all the time is not recommended because studies have shown the puppies fed this way consume 20 % more food and this may cause bone defects and obesity in later life.

The work could lead to regenerative treatments for patients with critical bone defects and soldiers who have suffered traumatic bone injuries.

Establishment of a preclinical ovine model for tibial segmental bone defect repair by applying bone tissue engineering strategies.

Platelet rich plasma - mediated delivery of BMP - 7 for segmental bone defect regeneration.

Delayed minimally invasive injection of allogenic bone marrow stromal cell sheets regenerates large bone defects in an ovine preclinical animal model.

Autologous vs. allogenic mesenchymal progenitor cells for the reconstruction of critical sized segmental tibial bone defects in aged sheep.

Electrospun nanofibers meshes for the repair of bone defects.

Biomimetic tubular nanofiber mesh and platelet rich plasma - mediated delivery of BMP - 7 for large bone defect regeneration.

The use of CRM and BMP specifically targeted areas of persistent bone defect after at least one failed surgery.

«Overall, the mandibular reconstruction program at UC Davis has been running for more than three years and has revolutionized the way we treat mandibular bone defects,» says Dr. Arzi.

Physicians have various approaches at hand to treat bone defects: Replacement material can come from a patient's own body, donated tissue, or a synthetic or naturally derived product.

Effects of Runx2 genetic engineering and in vitro maturation of tissue - engineered constructs on the repair of critical size bone defects.

The study, led by Darja Marolt, PhD, a NYSCF - Helmsley Investigator and Giuseppe Maria de Peppo, PhD, a NYSCF Research Fellow, and published in the Proceedings of the National Academy of Sciences, represents a major advance in personalized reconstructive treatments for patients with bone defects resulting from disease or trauma.

The stem - cell - derived bone tissue helped repair cranial bone defects in mice without developing tumors or causing infection.

Cohen says there are 40 000 cases of non-union fractures each year in the US, and more than 400 000 other bone defects and accidents that could be treated with the protein.

Cartilage and certain bone defects are notoriously difficult to heal.»

To treat a complicated, non-healing bone defect, surgeons often use an implant with living cells to promote bone repair, but the implanted cells have a small chance of surviving because they are not prepared for a lack of oxygen and nutrients at the fracture site.

To discover more regarding new stem cell therapies for improved bone defect repair, stay tuned to the Stem Cells Portal!

While bone grafts remain the best therapy for non-union bone defects, donor site morbidity and the limited availability of graft material represent significant obstacles for this treatment option [1].

BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical - sized long bone defects: A multiscale analysis.

The first eight projects target clinical areas such as bone defects, salivary glands, and skin wounds using a variety of regenerative methods, such as stem cells, biomaterial scaffolding, and harnessing regenerative signal secretion.

In vivo tracking of segmental bone defect healing reveals that callus patterning is related to early mechanical stimuli.

Preclinical animal models for segmental bone defect research and tissue engineering.

Researchers describe a new approach to improve in vivo osteogenesis by bone marrow - derived stem cells and thereby enhance bone defect repair strategies

Other occasionally reported symptoms are problems with internal organs, head and neck bone defects, partial deafness, alopecia, and luxated patellas (for more on this stifle problem, see my upcoming orthopedics book or some of the websites that carry my articles).

The disease retards growth and causes bone defects in children and makes them susceptible to a variety of cancers.

Particularly promising is additive manufacturing for biomedical applications, or additive biomanufacturing (ABM), where personalized and customized approaches can be developed through ABM to help surgeons and clinicians to treat patients with challenging problems ranging from large bone defects to deafness.

Delayed cell injection of allogenic mesenchymal progenitor cells for bone regeneration in an ovine critical - sized segmental tibial bone defect.

«We no longer have difficulties in regenerating bone across mandibular bone defects and, in most circumstances, dogs do not suffer from unstable jaw following cancer removal of non-healing jaw fractures.»

When transplanted into mice with bone defects, the osteoblasts formed new bone tissues in vivo without any signs of teratoma formation.

Ata has a range of bone defects that led to wild speculation that we had discovered an extraterrestrial.

However, the need for the rapid point - of - care clinical application of BM stem cells for bone defect repair will not allow for the purification of hMSCs from the BM, and so, the authors assessed the effect of transient BIO exposure to whole BM samples.

Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects.

A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists report today the generation of patient - specific bone substitutes from skin cells for repair of large bone defects.

While severity varies, bone defects and injuries are currently treated with bone grafts, taken either from another part of the patient's body or a donor bone bank, or with synthetic substitutes.

In future research, we will examine whether this technique also works in even larger bone defects and by using human cells.»

These encouraging data suggest that transient BIO treatment may represent a safe and rapid strategy to enhance the osteogenic potential of patient BM stem cells, a bone defect repair approach that the authors believe is a faster path to clinical translation than the treatment of purified and ex vivo - amplified hMSCs.

But he said: «One of the major problems facing scientists in this field is how to engineer a piece of bone with the right dimensions - that is critical for some of these bone defects.

Coating of biomaterial scaffolds with the collagen - mimetic peptide GFOGER for bone defect repair.

Microparticles for sustained growth factor delivery in the reconstruction of critical - sized segmental tibial bone defects.

«These experts work together to push the frontiers of technology, devising new ways to customise treatments for patients with challenging problems ranging from large bone defects to deafness.

Microparticles for sustained growth factor delivery in the regeneration of critically - sized segmental tibial bone defects.

An alginate - based hybrid system for growth factor delivery in the functional repair of large bone defects.

Dietary copper deficiency has been shown to cause bone defects and osteoporosis.

While not all regrowth surgeries are the same, the basic premise of the procedure is to place a scaffold (called a compression resistant matrix [CRM]-RRB- saturated with a bone morphogenetic protein (BMP) into the bone defect in hopes of stimulating additional bone growth from the surrounding, healthy native bone.

Two cases of infected, tibial nonunions are presented in which this technique was used to fill the bone defect created after sequestrectomy.

My understanding of the situation with osteochondrosis dissecans (OCD) is that there is an underlying bone defect that leads to the cartilage flap and that the bone defect is visible on radiographs.