Sentences with phrase «bone marrow cells called»

In a third of MDS cases, over time, very immature bone marrow cells called blasts may increase in number and fill the bone marrow, displacing the normal red and white blood cells and platelets that are produced there.

Not exact matches

In APL, immature white blood cells called promyelocytes increase in abnormal numbers and accumulate in the bone marrow.

Jerrold Olefsky and colleagues at the University of California, San Diego, killed the bone marrow cells in mice that make immune cells called macrophages.

They found that cyclophosphamide kills all of the donor's transplanted bone marrow cells except for stem cells containing high levels of an enzyme called aldehyde dehydrogenase (ALDH).

The investigators also discovered that neutrophils secrete a molecule called S100A8 / S100A9 that interacts with a receptor named RAGE (the Receptor for Advanced Glycation Endproducts) on bone marrow cells.

By studying the receptor for thrombopoietin, called Mpl, on blood cells in the bone marrow, the team pinpointed the cells involved in making platelets after thrombopoietin stimulation, and made an unexpected discovery.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

Then scientists reported that members of a class of RNA molecules called microRNAs direct the development of blood and bone marrow cells in mice.

In addition to suppressing the mature blood cells battling against the infection, malfunctioning of this signaling system results in permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marrow.

As a consequence of this so - called fibrosis, the bone marrow is no longer able to produce enough blood cells.

In experiments in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two weeks.

Hematopoietic stem cells — bone marrow - derived adult stem cells that give rise to the wide variety of specialized blood cells — come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates spawning billions of blood cells every day.

For example, they produce proteins called cytokines that tell infection - fighting immune cells to back off and recruit «suppressor» cells directly from the bone marrow that help cancel the immune attack.

These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.

All of them originate from cells in the bone marrow called stem cells.

In the study, USC Stem Cell researcher Casey Brewer and colleagues in the laboratory of Rong Lu found that transplantation dose affects the behavior of blood - forming stem cells in bone marrow — called hematopoietic stem cells, or HSCs.

In Germany, for example, the Munich - based biotech company apceth has already treated patients» gastrointestinal cancer with stem cells harvested from their own bone marrow and modified to convert a prodrug called ganciclovir.

Skin - specific dendritic cells called Langerhans cells originate in the bone marrow, but how they get to the skin, and how they maintain their numbers, had never been explained.

The so - called Stamina method is a treatment based on bone marrow stem cells that Stamina's President Davide Vannoni claims can grow new neurons under specific conditions and hence cure several neurodegenerative diseases.

It specifically affects antibody - producing white blood cells found in the bone marrow, called plasma cells.

But, it was known that when HIF - 1 normally activates signals in the body to build new vessels, one of the many types of cells recruited to the site of new vessel growth is a population of stem cells from the bone marrow, which are called bone marrow - derived angiogenic cells.

So researchers have been taking readily available and noncontroversial mesenchymal stem cells (also called bone marrow stromal stem cells that can form bone, cartilage and fat cells) and using a chemical process to turn them, or as researchers say, differentiate them into Schwann cells.

In addition, the cells in the blood and bone marrow (also called» myelo») usually look abnormal (or «dysplastic»), hence the name «Myelodysplastic» Syndromes.

To deliver the therapy, clinicians draw a group of cells called bone marrow mononuclear cells from patients» hips.

In that condition, stem cells collected from the blood or bone marrow could be removed from a patient, edited in the lab to correct the DNA typo — a process called «ex vivo» gene editing — and then reinjected to proliferate and make a patient healthy.

In addition to defects in blood stem cells, MDS is also affected by the cells that surround the stem cells in the bone marrow, the so - called stroma cells.

In patients with leukemia, immature cells called «blasts» overtake their healthy bone marrow.

Most stem cells are found in the bone marrow, although some, called peripheral blood stem cells, circulate in blood vessels throughout the body.

In more than 75 % of cases of RARS, the bone marrow cells have acquired a mutation in one particular gene called SF3B1.

B Cells - create Y - shaped proteins called antibodies and are developed in the bone marrow 2.

Blood cells are produced in the center spongy part of the bone called the marrow.

Stem cells that live in that bone marrow produce a specialized white blood cell called a B cell.

We can cause these stem cells to leave the bone marrow (with a medication called Neupogen) and travel out into the peripheral blood, where we can collect them using a sophisticated apheresis machine.

It's called Panleukopenia because of how the virus will temporarily wipe out the infected cat or kitten's bone marrow of the precursor cells that produce white blood cells, red blood cells, and platelets.

I think that probably the signs of pano or the actual development of enostosis, as some prefer to call it, in the hemophiliac dog come about via bleeding in the marrow with osteoblast (bone depositing cells) activity.

It is also called panleukopenia as it affects the bone marrow and causes low white blood cell counts.

Part of the hemoglobin molecule is recycled to the bone marrow to be incorporated into new red blood cells (also called erythrocytes or RBCs).

The tumors appear as sold growths which begin in the lymph nodes or bone marrow or as individual cells freely circulating in the blood, in which case they are called leukemia.

In addition to increased thirst and urine volume (often called PU / PD, meaning polyuria and polydipsia) over time a cat with CRD may become anemic, since the kidneys produce a hormone that stimulates the bone marrow to produce red blood cells.

The bone marrow should respond to anemia by producing more red blood cells; therefore, an increase in the number of immature cells called reticulocytes should be seen on lab results.

A synthetic hormone called Epogen (erythropoietin) can be used to stimulate the bone marrow to produce red blood cells.

Screening blood work, commonly called a «panel and CBC» measures the function of all the internal organs including the liver, kidneys, pancreas, bone marrow production of white and red blood cells and platelets.