Sentences with phrase «boost vaccine candidate»

These new preclinical studies provide support for advancing the Ad26 / MVA prime - boost vaccine candidate into clinical development.

Glenda Gray, executive director of the Wits Health Consortium's perinatal HIV research unit in South Africa, presented data today at the HIV R4P conference in Cape Town indicating that the prime - boost vaccine candidates initially tested in the RV144 trial in Thailand — the only HIV vaccine trial to date to show any efficacy — induced cross-clade immune responses in a Phase I safety trial conducted in South Africa, with immunogenicity similar to or greater than that of the responses induced in Thai volunteers.

Not exact matches

TNA8: BPRC will provide access to macaques for immunogenicity / adjuvanticity evaluation of vaccine candidates for malaria, tuberculosis, HIV, influenza, West Nile virus or dengue virus, with up to three (prime - boost) immunisation events.

A vaccine that boosts levels of anti-AMA1 antibodies might therefore reduce the risk that malaria infection will cause clinical disease, making AMA1 an attractive candidate for inclusion in a multi-stage, multi-antigen malaria vaccine [8].

As part of this upcoming study, some Ugandan volunteers from the 2009 DNA study will receive a boost, or additional injection, with the new vaccine candidate to explore a more long lasting effect of vaccination.

The panel discussed progress that's been made including the follow - up to the RV144 Thai prime - boost trial results and in the development of the next generation of vaccine candidates for testing.

A004 is a phase II study of an HIV candidate vaccine Ad26 prime with MVA and protein boost funded and sponsored by Janssen, a division of J&J.

«This study allowed us to evaluate the protective efficacy of several prime - boost vaccine combinations, and these data will help guide the advancement of the most promising candidates into clinical trials,» noted lead author Dr. Dan Barouch of Beth Israel Deaconess Medical Center at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard.

Study results, presented at the 2009 AIDS Vaccine Conference, suggest that MVA - CMDR is an ideal candidate for future prime - boost vaccination strategies.