Sentences with phrase «both by immune cells»

If the pathogen or parasite gets by these immune cells, it may successfully invade the mosquito salivary glands.

Ferumoxytol leaks out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

The experiments indicated that when dectin - 1 recognizes tropomyosin in house dust mites, shrimp or other common allergy - triggering species it suppresses airway cells» production of an immune molecule, IL - 33, which otherwise would promote an allergic response by immune cells.

Outside of the brain, cytokines are released by immune cells fighting infections, and they can alter MHCI expression in a complicated feedback loop.

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving.

In lab tests, the CpG - antigen package, at 300 nanometers in size, was absorbed 90 percent of the time by immune cells, the UI - led team reports.

Patients can succumb to bacterial infections because their immune systems lack a molecule required by immune cells, specifically neutrophils, to go to the site of infection.

Further experiments suggested that the production of high levels of cell wall - associated GAG makes A. fumigatus more resistant than A. nidulans to neutrophil killing by neutrophil extracellular traps, or NETs (NETs are are networks of extracellular fibers, composed of DNA and proteins secreted by immune cells called neutrophils, that bind and trap various pathogens).

Slusher teamed up with Johns Hopkins Kimmel Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune cells.

Particularly prominent in the RNA - Seq analysis was the up - regulation of a number of granzymes, a group of proteinases secreted by immune cells that were originally thought to be involved in killing (via apoptosis) virus infected cells or other target cells.

They have identified a «checkpoint» manned by these immune cells that, if barred, can halt the development of the lung inflammation associated with allergies.

The Harvard researchers began by analysing the three - dimensional structure of the small region of the nerve cell sheath protein that is targeted by immune cells in MS patients.

Mammals are known to fend off viruses with a system based on interferons, signaling proteins made by immune cells that amplify the body's attack on invaders.

Not only are they produced by immune cells, they are also produced by cells whose functions are not immune - related.

«The nanoparticle mimics the behavior of NADPH oxidase, an enzyme used by immune cells to kill tumor cells and infectious agents.

Most of the time when the heart is injured, these beneficial immune cells are supplanted by immune cells from the bone marrow, which are spurred to converge in the heart and cause inflammation that leads to further damage.

The main role here is played by immune cells migrating from the blood into the tissue to fight the inflammation.

Some have proposed that age - associated inflammation is caused by accumulating wear and tear on our immune cells, while others have suggested that it is caused by immune cells dealing with chronic viral infections.

«New potential cause for Alzheimer's: Arginine deprivation caused by overconsumption by immune cells.»

IL - 6 is a cytokine, a signal molecule that is produced and secreted both by immune cells and by tumor cells and binds specifically to a receptor (IL - 6R) that is found on the surfaces of many cell types.

Building on that work, the current paper looked at a less lethal strain, the H1N1 «swine flu,» that does not infect neurons, but which, the researchers showed, still caused inflammation in the brain via inflammatory chemicals or cytokines released by immune cells involved in fighting the infection.

The patients without diabetes produced autoantibodies that completely impaired the activity of a subtype of interferon known as interferon - alpha, which is produced by the immune cells and may cause inflammation.

In animal studies, exosomes secreted by immune cells during environmental enrichment caused cells in the brain to start myelin repair.

It is also released by immune cells in inflamed tissues.

Resolvins are made from an omega - 3 fatty acid by your immune cells.

Cortisone helps to enhance the barrier function of the endothelium, preventing vascular leakage and further infiltration of the alveolar space by immune cells.

Resolvin D - 1 is a bioactive mediator produced by immune cells for cell - to - cell signaling, and it is part of the natural innate immune response that resolves inflammation.

In the brain, a synapse (orange) is seen being wrapped around and attacked by immune cells called microglia (green), leading to synapse loss.

The altered methionine metabolism leads to activation of oncogenes, while the changes in tryptophan metabolism shield GBM cells from detection by immune cells.

«Brain cancer cells are very good at evading the host immune system, because they do not express specific targets that can be recognized by immune cells,» said Liau, professor and vice chair of neurosurgery.

Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about one percent of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen.

It then passes through the intestinal wall and is met by immune cells that would normally kill it.

Scientist at the University of Bonn and TU Munich have now discovered that type I IFN released by immune cells due to increased migration of gut bacteria into the cirrhotic liver incapacitate the immune system.

Too large a dose can cause congestive heart failure, among other side effects, while a small dose may be overwhelmed by immune cells, which consider doxorubicin a foreign invader.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

«The destruction of red blood cells outside of vessels by immune cells in PNH has long been speculative due to limited experimental evidence.»

The molecule, called microRNA 29b, would be ineffective if delivered by injection alone, as it quickly becomes degraded in the bloodstream or picked up and removed by immune cells.

In a typical immune response, for instance, inflammatory proteins called cytokines will be released by immune cells at a site of inflammation and then other immune cells will use these cytokines like a trail of breadcrumbs to home in on the site of infection and destroy the pathogens that are causing it.

The main role here is played by immune cells migrating...

Although immunology covers all aspects of this complex network, the field is united by the immune cell.

Mouse studies showed that bacteria without the ICL gene starve and are finished off by immune cells.

This appears to involve direct infection of Sertoli cells and germ cells which then results in a series of changes, such as cell death and invasion by immune cells, and pronounced inflammatory - like changes within the testes.

These «surface proteins» are easily recognized by the immune cells and targeted for destruction.

Cytokines are the main chemical signals of inflammation, secreted by immune cells in emergencies, and all these actions are part of the usual defensive strategy (in constant evolution) that our body applies at all times.

The favorable results are due in large part to the advances in managing severe graft versus host disease (GVHD), an attack on the patient's normal tissues by immune cells of the donor.

11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance Findings may have important potential for new drug discoveries in fight against Type 2 diabetes Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrop... More...

Once these nanoparticles are taken up by immune cells, the tumor proteins attached to their surface can help immune cells recognize identify cancer cells across body.

To me it seem like plaques form when the blood becomes «saturated» with cholesterol and it «precipitates» out in the walls of the arteries where it is eaten by immune cells which turn into foam cells when they become engorged with cholesterol.

Also, while ketones can replace glucose as a fuel, they can not glycosylate proteins, or generate ROS in the manner needed by immune cells.