His approach to the top of the tree (home to eukaryotes, which wrap their DNA in membrane -
bound cell nuclei) would rule biology classrooms for decades.
Not exact matches
A few years ago, Snyder's team and other researchers found that if NO reacts with GAPDH, GAPDH can then
bind to another protein that whisks GAPDH away from its humdrum sugar metabolism tasks and into the
nucleus, the
cell's control center.
This is because yeast is eukaryotic: its
cells have a membrane -
bound nucleus that contains the genetic material, whereas bacteria are prokaryotic and do not.
Vitamin A and vitamin D are precursors to hormones that influence biological processes by entering the
nucleus of a
cell,
binding to DNA, and altering the transcription of certain genes.
Disease processes often begin with mutations in the transcription factor, or in the DNA they
bind to inside the
nucleus of
cells to regulate the complex interplay of genes needed for a healthy functioning body.
«We demonstrated that alpha - KGDH interacts with Gcn5 in the
cell nucleus and found that tumor
cell proliferation and tumor growth were inhibited when alpha - KGDH was blocked from entering the
cell nucleus or by disruption of Gcn5's
binding to succinyl - coenzyme A,» said Lu.
Choudhury and colleagues designed a series of experiments to find that DAZAP1
binds to a number of other proteins in the
cell nucleus and promotes alternative splicing.
They work by
binding to receptors inside a
cell, which then travel to the
nucleus and act on the DNA by turning select genes on and off.
Kiebler and his group had previously shown that the brain - specific RNA -
binding protein Staufen2 (Stau2) plays a central role in the transport of mRNAs from the
cell nucleus to synaptic ribosomes.
The genes for each transcription factor were made from different bits of DNA that code for the functional parts of proteins, such as a domain that can
bind to DNA and another that provides the protein with access to the
cell's
nucleus.
Bacteria and Archaea, while genetically distinct, are both Prokaryotes, single -
celled organisms lacking a membrane -
bound nucleus.
SATB2 is a DNA -
binding protein that facilitates structural organization of chromosomes in the
nucleus of
cells.
The Archaea domain consists of single -
cell microorganisms that, like bacteria, have no
cell nucleus or membrane -
bound organelles, a sub-unit within a
cell.
This visualization shows tightly - packed DNA in a mouse
cell's
nucleus at different stages of development, seen here in a semi-triangular form as a mature nerve
cell; in a roundish shape as a multipotent stem
cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized
binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.
Here, we report that unphosphorylated STAT6 is present in the
nucleus and may facilitate constitutive COX - 2 expression in NSCLC
cells via
binding to the COX - 2 promoter in association with p300.
Calcitriol mediates its biological effects by
binding to the vitamin D receptor (VDR), which is principally located in the
nuclei of target
cells.
The hormone enters the
cell, attached to a receptor, and then enters the
nucleus of the
cell where it
binds directly to the DNA.