Not exact matches
So the researchers turned to a machine made by Quanterix of Lexington, Massachusetts, that uses
magnetic beads coated by an antibody that
binds selectively and extremely tightly to the protein in the blood.
Each is composed of building blocks
bound together, like a string of small
magnetic beads — and just as magnets have poles, these building blocks have «plus» and «minus» ends.
A team led by the Hutch's Marie Bleakley and by Warren Shlomchik of the University of Pittsburgh School of Medicine in Pennsylvania removes naïve T cells from grafts with a
magnetic system that uses monoclonal antibodies
bound to iron
beads.
They added these
beads to the sample to be tested, and then added that mixture to a test tube containing
magnetic beads coated with DNA strands that
bind the other half of the DNA.
The kit adopts a novel purification method, using
magnetic beads and phosphatidylserine -
binding protein to isolate exosomes and other EVs from cell - culture medium and body fluids by a normal microcentrifuge.
Using a proprietary protocol DNA fragments are
bound directly onto the surface of the
magnetic beads, leaving unincorporated nucleotides, primers, primer dimers, and other contaminants in solution.
With MagSi - Direct, you can start with a molecule of interest, attach
magnetic beads to it and then use a magnet to isolate that molecule from any desired reaction mixture, together with any other molecules, complexes or even intact cells to which the starting molecule has
bound.
Using the new solution, DNA fragments are
bound directly onto the surface of the
magnetic beads, leaving unincorporated nucleotides, primers, primer dimers, and other contaminants in solution.