Sentences with phrase «brain atrophy in»

While the relationship between age and brain atrophy in humans is well documented and could potentially bias a comparison between different age groups, there is no evidence that this is the case in dogs (a recent study has shown that Labradors in the age groups 1 — 5, 5 — 10 and 10 + have similar cerebellar volumes)[22] or even chimpanzees [25].

Studies have found blood glucose levels even at the normal range can have a significant impact on brain atrophy in aging.

This result corresponds with earlier findings that vitamin B supplements slow the rate of brain atrophy in mild cognitive impairment only in individuals with a good Omega - 3 level to begin with.

Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease

To determine whether supplementation with B vitamins that lower levels of plasma total homocysteine can slow the rate of brain atrophy in subjects with mild cognitive impairment in a randomised controlled trial (VITACOG, ISRCTN 94410159).

First, in studies over longer periods (up to 5 years) it has been found that the rate of whole brain atrophy in MCI is correlated with cognitive decline in several tests, including the MMSE [5].

Bilingualism as a contributor to cognitive reserve: Evidence from brain atrophy in Alzheimer's disease.

The accelerated rate of brain atrophy in elderly with mild cognitive impairment can be slowed by treatment with homocysteine - lowering B vitamins.

Cross-Sectional and Longitudinal Relationships between Depressive Symptoms and Brain Atrophy in MS Patients

Auriel Willette, a researcher in food science and human nutrition, found evidence that an elevated presence of a protein called neuronal pentraxin - 2 may slow cognitive decline and reduce brain atrophy in people with Alzheimer's disease.

Auriel Willette, a researcher in food science and human nutrition at Iowa State University, found evidence that an elevated presence of a protein called neuronal pentraxin - 2 may slow cognitive decline and reduce brain atrophy in people with Alzheimer's disease.

Not exact matches

There have been studies linking brain atrophy with born - again / later - in - life religious conversions.

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

«Amyloid is one of many substances that builds up in plaques as a result of dying cells and atrophy in the brain,» he says.

Moreover, researchers found that the aging brain's failure to coordinate deep - sleep brainwaves is most likely due to degradation or atrophy of the medial frontal cortex, a key region of the brain's frontal lobe that generates the deep, restorative slumber that we enjoy in our youth.

At the end of the second phase, the rate of brain atrophy had also slowed in presymptomatic participants that started taking creatine after 6 months on placebo.

The disease is caused by a genetic mutation that leads to abnormal clumps of protein in the brain, eventually resulting in the atrophy and death of nerve cells.

Most of the recent PTSD imaging studies have found atrophy only in the hippocampus; the rest of the brain is fine.

And a third brain region has attracted a lot of attention recently because it may atrophy in response to a certain type of serious stress.

Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.

But I can still write a pretty good sentence, heartened that the cognitive decline that might be expected to accompany the brain's atrophy is neither linear nor predictable, partly because older brains compensate by forging workarounds in connectivity.

Recent research also has illuminated how the deadly cascade that leads to brain atrophy is set in motion: The buildup of amyloid plaques, working in tandem with certain gene mutations, sparks the formation of the renegade tau proteins.

«It was particularly exciting to see plasticity in the neurons impaired by mHTT,» said Davidson, noting that in the HD mice, brain areas that had begun to atrophy recovered volume and permitted better motor function after the researchers restored mTORC1 activity to more normal levels.

In 78 brain regions, they factored in the pattern of amyloid concentration, glucose metabolism, cerebral blood flow, functional activity and brain atrophIn 78 brain regions, they factored in the pattern of amyloid concentration, glucose metabolism, cerebral blood flow, functional activity and brain atrophin the pattern of amyloid concentration, glucose metabolism, cerebral blood flow, functional activity and brain atrophy.

He also found that participants with higher levels of inflammatory proteins in their cerebrospinal fluid showed modestly greater memory loss and brain atrophy over two years.

He was a veteran professional football player, in his mid-60s when he died, and a paper - thin cross section of his brain tissue taken at the autopsy appears visibly shrunken and atrophied.

In July Schiff and his colleagues reported that Wallis's brain was badly atrophied — but it had not been idle.

These changes may be linked to atrophy and volume loss in the brain's grey matter, according to the researchers.

Our main measure of success was to reduce the rate of brain atrophy,» explains study leader Dr Jeremy Chataway of University College London Hospitals / UCL in the UK.

After analyzing their MRIs over the following years, Lin and his colleagues, reporting in an upcoming issue of Neuroimage, say those participants whose hearing was already impaired at the start of the sub-study had accelerated rates of brain atrophy compared to those with normal hearing.

«Atrophy of the hippocampus, a region of the brain crucial for memory, is a common feature of AD, although it may also be detected in asymptomatic individuals as well as healthy adult carriers of the ApoE ɛ4 allele,» explained Andy Simmons, PhD, of the Department of Neuroimaging of the Institute of Psychiatry of King's College London.

A case in point is the rare but severe psychomotor disease Allan - Herndon - Dudley syndrome (AHDS), a congenital condition that affects only males and starves the developing brain of thyroid hormone, resulting in cognitive impairment and atrophied muscles and motor skills.

«A healthy lifestyle, such as participating in lifestyle physical activity, is beneficial for brain health, and may help lessen gray matter atrophy (decreases).»

The new approach, published today in the International Journal of Stroke, can quantify visible brain injury from cerebral small vessel disease (SVD) and brain atrophy by translating the million plus bits of information stored in brain scans into a single measure, the «brain health index.»

Namely, they investigated language and cognition control areas in the frontal regions of the brain, and medial temporal lobe structures that are important for memory and are brain areas known to atrophy in MCI and AD patients.

This disorder is marked by the loss of motor neurons in the brain and spinal cord, and atrophy of the frontal and temporal lobes.

mThy1 - AS mice administered only control IgG1 suffered dendritic atrophy (as suggested by reduced staining with MAP2) and synaptic loss (evaluated with postsynaptic density - 95 (PSD - 95) and synaptophysin) across several regions of the brain, but this neurodegenerative damage was substantially prevented in mice administered 1H7, 5C1, or 9E4.

Although most infants had microcephaly by head circumference measure, some patients had a measurement that was consistent with their gestational age, as brain atrophy was compensated by an enlargement in ventricular size.19

The mean perpendicular edge motion across the entire brain surface produces a change image that can be converted into estimates of rate of atrophy reflecting changes in both grey and white matter [31].

SCI has also been correlated with brain changes such as hippocampal atrophy (shrinkage due to cell death in this area of the brain).

The observation in the placebo group that the rate of atrophy was related to the baseline concentration of tHcy is consistent with, and may explain, a number of cross-sectional studies reporting that regional brain atrophy is related to tHcy [17], [18], [19], [20], [21].

It was atrophy of a brain area, which is a normal consequence of aging, that was involved in generating deep sleep.

Chronic stress appears to block a gene that guards against brain atrophy associated with depression, according to a study in...

We show that a simple and safe treatment that targets homocysteine can slow down the accelerated rate of brain atrophy found in mild cognitive impairment.

Thus, brain atrophy rate appears to be a major determinant of cognitive decline in this population.

An increased rate of brain atrophy is often observed in older subjects, in particular those who suffer from cognitive decline.

Salsalate successfully reversed these effects in a mouse model of FTD, lowering tau levels in the brain, rescuing memory impairments, and protecting against atrophy of the hippocampus — a brain region essential for memory formation that is impacted by dementia.

B vitamin treatment led to a difference in final tHcy concentration of 31.7 % compared with the placebo, and was accompanied by a reduction in the rate of brain atrophy of almost 30 %.

The mean rate of brain atrophy per year was 0.76 % [95 % CI, 0.63 — 0.90] in the active treatment group and 1.08 % [0.94 — 1.22] in the placebo group (P = 0.001).

Scientists are discovering that age - related changes in the brain such as atrophy, synapse loss and free radicals may contribute to AD, as does genetics.