Sentences with phrase «brain barrier disruptions»

High Vitamin C supplementation reduces amyloid plaque deposition (cause of AD), blood brain barrier disruptions and mitochondrial dysfunction in the brains.

Furthermore, blood - brain barrier disruption provoked immediate and focal activation of microglia, switching their behavior from patroling to shielding of the injured site.

Cerebral mast cells mediate blood - brain barrier disruption in acute experimental ischemic stroke through perivascular gelatinase activation.

Cellular mechanisms of IL -17-induced blood — brain barrier disruption.

Human TH17 lymphocytes promote blood — brain barrier disruption and central nervous system inflammation.

Did you know that cell phone radiation has been scientifically linked with brain cancer, blood - brain barrier disruption (AKA «leaky brain»), depression, anxiety, premature aging, insomnia and infertility?

Several candidate mechanisms of CRCI have been proposed, including inflammation and cytokine dysregulation, chemotherapy - induced epigenetic changes, blood — brain barrier disruption, hormone deficiencies, oxidative DNA damage and shortened telomere length, and genetic susceptibility.21 — 26 However, the heterogeneity and design limitations within the emerging body of evidence have led to recommendations for harmonising study methodologies and moving towards multisite, longitudinal research.3 27 Such approaches would support the demonstration of robust relationships between measurable biological processes and cognitive outcomes.

Not exact matches

Previous research had shown that certain eye diseases could cause a similar disruption to the blood - ocular barrier, which does for the eye what the blood - brain barrier does for the brain.

This causes inhibition of glucose uptake and the disruption of the blood - brain barrier integrity.

«Blood clotting protein triggers immune attack on brain: Disruption of the blood - brain barrier triggers a cascade of events that results in autoimmunity, brain damage characteristic of multiple sclerosis.»

Through a series of sophisticated experiments, researchers reporting in The American Journal of Pathology suggest that matrix metalloproteinase - 3 (MMP - 3) plays a pivotal role in disruption of the brain / spinal cord barrier (BSCB), cell death, and functional deficits after SCI.

Excessive proteolytic activity of MMPs can be detrimental, leading to numerous pathological conditions, including blood brain barrier (BBB) / BSCB disruption after injury,» explains Tae Young Yune, PhD, of the Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.

Chemicals like DEET and permethrin can enter the brain through disruption of the blood - brain barrier, where they can inhibit the breakdown of a neurotransmitter called acetylcholine.

Last year, Dr. Akassoglou and her team found that a key step in the progression of MS is the disruption of the blood brain barrier (BBB).

PCI, on the other hand, allows for targeted disruption of the barrier by combining light activated drugs, or photosensitizers, with drugs known to disrupt the blood - brain barrier.

Disruption of the blood - brain barrier triggers a cascade of events that results in autoimmunity and brain damage characteristic of multiple sclerosis

In this study we have identified the disruption of the blood - brain barrier following inflammatory and vascular injury as a mechanism of disease.

«Ultrasound, with all of its good qualities, is disruptive to the blood - brain barrier, whereas we can get an agent to cross it without causing disruption,» Connor said.

However, the ultrasound causes temporary disruption to the blood - brain barrier which allows not only the therapeutic agent to enter the brain, but also blood which could have medical implications.

Disruption of brain barrier results first in the release of BBB proteins and then in the formation of IgG, IgM or IgA antibodies against tight junctions and BBB proteins.

This reflects growing interest in the extent to which excessive activation of stress response systems can lead to disruptions in developing brain architecture that create barriers to learning, as well as impairments in other maturing organs and metabolic regulatory functions that lead to lifelong problems in health.