Sentences with phrase «brain cell samples»

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Not exact matches

The approach is particularly helpful for producing cells that can not be obtained from patient samples, such as brain cells.

HBI member V. Wee Yong, PhD and research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are compromised.

The researchers tested samples of brain cells from people with MS and healthy control subjects and found evidence of the virus in the olfactory bulb in both groups.

The team looked for these cells in nonliving brain samples in two ways: molecular markers that tag dividing cells and young nerve cells, and telltale shapes of newborn cells.

Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain endothelial cells.

In addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain samples.

Over the course of three years, Horvath and his team analyzed nearly 8,000 tissue samples from these datasets, which included blood, saliva and cells from organs like the brain and the colon.

A small skin sample from a person with bipolar disorder can yield stem cells that can be coaxed to become neurons just like those in the brain.

They confirmed low levels of miR - 184 expression in human glioma tissue samples and cultured cell lines as well as an increase in the expression of SND1 compared to normal brain tissue.

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first.

The Raman images now show protein activity at neural cell level, but the sensitivity is high enough for detecting areas that are even smaller — as is the case with the brain sample of the healthy person.

She and colleagues examined DNA from individual brain cells taken from three donated human brains and tested bulk samples from the hippocampus (an area important for learning and memory) and the frontal cortex (where most thinking and decision making is thought to happen).

Working with the brains of six normal children and seven autistic children ages 2 to 16, most of whom died of drowning, Courchesne has studied neurons under the microscope and even counted the number of neural cells in different tissue samples.

The study of human astrocytes has faced issues related to access (samples of living tissue must be obtained from brain cancer or epilepsy surgeries or fetal tissue) and purification (breaking apart astrocytes away from other cells often killed them and many experiments ended in failure).

Twenty - four hours after the injection, the researchers saw large numbers of immune system white blood cells in tissue samples of the rodent brains near the site of injury of those mice injected with the cytokine IL - 1b, but not in the brain tissue of the control group of mice.

Still, when the brain cells and spinal cord cells of these babies were examined at autopsy, there was clear evidence that nusinersen had tricked SMN2 into producing a great deal more of the full length, motor neuron - protecting protein: two to six times more copies of SMN's messenger RNA were found in spinal cord samples from nusinersen - treated babies than in autopsy samples from untreated infants.

Scientists at the University of Luxembourg have succeeded in turning human stem cells derived from skin samples into tiny, 3 - D, brain - like cultures that behave very similarly to cells in the human midbrain.

The researchers counted the numbers of a particular type of immune cell, known as microglia, in the samples and found that these were more numerous in the brains with Alzheimer's disease.

3/24/2008 Non-Invasive Imaging Provides Window Into Genetic Properties of Brain Tumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surBrain Tumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surbrain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.

There are many more glial cells in the brain than neurons, and astrocytes are the most abundant of the glia, so if you take a sample of brain tissue, you're fairly sure to get some astrocytes as part of the bargain.

Due to the heterogeneous structure of the brain, with many nuclei and cell - types organized in complex networks, it is difficult to achieve a comprehensive overview in a 1 mm tissue sample.

This process is particularly useful to recreate cells from organs like the brain, which can't be sampled from a living individual.

The benefits of using olfactory receptor neuron samples to study psychiatric disorders and patient responsiveness include their similarity to brain neurons, the relatively easy biopsy procedure, and the potential for scientists to sample and compare cells from the same patients throughout several different stages of disease.

To overcome this problem, the researchers utilized a method that involved dissolving the cell membranes in order to create a sort of «brain soup» so that they can then count the number of cell nuclei in a sample.

ApoE4 causes a dramatic reduction in SirT1, as seen in both neuron cells and in brain samples from people with AD.

Stem cells allow researchers to collect blood or skin samples from living patients and turn them into the brain cells affected by the disease — neural progenitor cells (NPCs) and neurons.

Sampling brain tissue is way too risky in living subjects for obvious reasons, and it's difficult to isolate causes and effects in the brain after death because there are so many factors that can contribute to the condition of the cells.