Sentences with phrase «brain cell survival»

«Speedy restoration of blood flow to the brain is crucial for brain cell survival everywhere.»
Furthermore, when healthy neurons in a dish were treated with serum from the patients and antibodies against leiomodin - 1, they did not survive, but removing the antibodies increased brain cell survival.

Not exact matches

«In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock said.
Triple negative patients usually have shorter survival time after diagnosis of brain metastasis, suggesting that these tumor cells adapt much more readily once they've moved to the brain.
Boldrini says that future research on the aging brain will continue to explore how neural cell proliferation, maturation, and survival are regulated by hormones, transcription factors, and other inter-cellular pathways.
In many patients diagnosed with LUAD, tumors cells have already spread to the brain, leading to decreased quality of life and low survival rates.
Again, using mouse models of glioblastoma — this time created from brain tumor cells that were resistant to the herpes virus — the therapy led to increased animal survival.
The investigators report that trapping virus - loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiforme, the most common brain tumor in human adults and also the most difficult to treat.
They cross the blood - brain / blood - tumor barrier, and accumulate within brain tumor sites, where they target oncogenes, regulate cell growth and differentiation, reduce tumor burden and prolong survival in our mouse models.»
Dr. Massagué is particularly interested in the ability of tumor cells to hug blood vessels, as he suspects this behavior may be essential for the survival of metastatic cancer cells not only in the brain but also in other parts of the body where metastatic tumor growth can occur.
GLP - 1 receptors are also found in the brain, and prior research has shown that activating them can boost the function of dopamine connections, act as an anti-inflammatory, improve energy production, and switch on cell survival signals.
By assessing the survival of the cells that engulf the particles and measuring the levels of red or green light that they emitted, the researchers determined which formulation of particles performed best, then tested that formulation in mice with human brain cancer derived from their patients.
However, this is the first time these biodegradable nanoparticles have effectively killed brain cancer cells and extended survival in animals.
SMA is caused by a mutation in a gene that is vital for the survival of nerve cells that connect the brain and spinal cord to the muscles, known as motor neurons.
«Lithium chloride is known to block many pathways that lead to brain cell death, while promoting others that lead to survival, like brain - derived neurotrophic factor, or BDNF,» says Saito, a research assistant professor at NYU Langone.
Astrocytes, one type of glial cells are the supporting cells for survival and function of neurons in the brain by secreting many kinds of neuroprotective molecules.
Investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute have developed an imageable mouse model of brain - metastatic breast cancer and shown the potential of a stem - cell - based therapy to eliminate metastatic cells from the brain and prolong surviCell Institute have developed an imageable mouse model of brain - metastatic breast cancer and shown the potential of a stem - cell - based therapy to eliminate metastatic cells from the brain and prolong survicell - based therapy to eliminate metastatic cells from the brain and prolong survival.
In vitro, transforming human brain neuroglioma or Chinese hamster ovary cells with an amyloid - β isoform resulted in better survival following a yeast infection.
Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival.
Long - term survival in patients with non-small cell lung cancer and synchronous brain metastasis treated with whole - brain radiotherapy and thoracic chemoradiation.
• Keeping abnormal proteins from building up and potentially shutting down major organs (heart, liver and nervous system, to name a few) • Protecting the brain's functions of learning and memory against neurotransmitter toxicity • Activating or increasing the activity of proteins that promote the initial growth, maintenance and survival of brain neurons • Enhancing the movement of proteins, lipids and other cell parts through the cytoplasm of cell bodies.
Boldrini says that future research on the ageing brain will continue to explore how neural cell proliferation, maturation, and survival are regulated by hormones, transcription factors, and other inter-cellular pathways.
Recent studies reported that gestational nicotine exposure modulates the cell - adhesion and cell - death / survival systems in the brains of adolescent rats and may lead to numerous behavioral and physiological deficits [41], [42].
How the other great apes lost the cells remains unknown, but the researchers theorize genetic disruptions affecting the cells» migration to different parts of the brain, differentiation, or survival could have led to the loss.
This program has provided the first comprehensive picture of how a gene normally associated with cancer can influence development, survival and normal function of brain cells central to age - associated neurodegenerative disorders such as Parkinson's disease.
Studies in rats have shown that physical exercise boosts BDNF (brain - derived neurotrophic factor — a molecule that promotes the growth and survival of brain cells) levels in the hippocampus, which is a brain structure crucial for learning and memory formation.
Exercise also increases the generation of neurochemicals, such as IGF - 1 and BDNF, which promote growth, survival, differentiation and repair of brain cells.
Brain - derived neurotrophic factor (BDNF) is a protein supporting the survival, function and growth of brain cBrain - derived neurotrophic factor (BDNF) is a protein supporting the survival, function and growth of brain cbrain cells.
It effects every tissue in your body including the uterus, cervix, and vagina, the endocrine (hormonal) system, brain cells, fat metabolism, thyroid hormone function, water balance, peripheral nerve myelin sheath synthesis, bone cells, energy production and thermogenesis, the immune system, survival and development of the embryo, and growth and development of the fetus.
IGF - 1 also acts as a neurotrophic factor in the brain, contributing to neurogenesis (growth of new brain cells) and survival of existing neurons, along with better cognitive function.
alertness, awareness, mood, sleep, smell, brain growth, cell survival, and social recognition.
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Lithium might also protect the brain from numerous damaging compounds by increasing bcl - 2, a protein that may improve the survival of brain cells even possibly from damage cause by a stroke.
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