Sentences with phrase «brain cells in the laboratory»

A group of really brainy scientists have moved closer to growing «therapeutic» brain cells in the laboratory that can be re-integrated back into patients» brains to treat a wide range of neurological conditions.

Not exact matches

Using these cells, the team modeled the patients» neurons and blood - brain barrier in a laboratory dish.

According to the latest studies from the fly laboratory of California Institute of Technology (Caltech) biologist David Anderson, male Drosophilae, commonly known as fruit flies, fight more than their female counterparts because they have special cells in their brains that promote fighting.

Scores of laboratories at universities and in private industry are uncovering how to use these cells, which transform into neurons, astrocytes (the cells that regulate transmission of electrical impulses in the brain) and oligodendrocytes (which insulate nerve fibers with a fatty coating).

Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain endothelial cells.

Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.

But this came from work in my laboratory and others that suggested that nerve cells in affected regions of the Alzheimer brain looked like they were trying to divide.

«Activation of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the GUMC Translational Neurotherapeutics Program.

In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuIn a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the adult mouse hippocampus.

«This lets us keep age - related signatures in the cells so that we can more easily study the effects of aging on the brain,» says Rusty Gage, a professor in the Salk Institute's Laboratory of Genetics and senior author of the paper, published October 8, 2015 in Cell Stem Cell.

Detlev Arendt and Joachim Wittbrodt, developmental biologists at the European Molecular Biology Laboratory in Heidelberg, Germany, jumped into the fray after Arendt noticed some vertebrate - like photoreceptor cells in the brains of ragworms, a marine species that hasn't changed much for 500 million years.

In both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cellIn both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cellin Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cellin forming the brain and nerve cord divide into three columns of cells.

Orit Matcovitch - Natan, a graduate student in the laboratories of both Amit and Schwartz, and other members of the two teams, studied the sole immune cells present in the brain — the microglia, which contribute to the brain's development and maintenance.

«For example, there is a huge amount of interest and excitement globally in growing cerebral organoids» — miniature brain - like organs that can be studied in laboratory experiments — «from stem cells to model human brain development and disease mechanisms.

A recent generation of studies of postmortem brain tissue from people with schizophrenia, particularly from the laboratory of Professor David Lewis and his colleagues at the University of Pittsburgh, have shed light on schizophrenia - related abnormalities in the interplay of the main excitatory neurons, pyramidal neurons, and a specific class of inhibitory nerve cells, called chandelier cells, in the prefrontal cortex.

New research by neuroscientists at Cold Spring Harbor Laboratory (CSHL), published in The Journal of Neuroscience, reveals a set of cells in the fruit fly brain that respond specifically to food odors.

A previous study, published in 2013 in PLOS Biology by auditory neuroscientist Andrew King and his laboratory at the University of Oxford in England, showed that brain cells can enhance the gain of their responses, increasing the signal corresponding to the sound of interest, while tuning out the noise.

After introducing stem cells in brain tissue in the laboratory and seeing promising results, Prof. Offen leveraged the study to mice with Alzheimer's disease - like symptoms.

iPSC are made from patient skin cells rather than from embryos and can become any type of cells, including brain cells, in the laboratory.

Researchers demonstrated that the drugs pemetrexed and gemcitabine killed cells from mouse and human brain tumors, called group 3 medulloblastoma, growing in the laboratory.

Asst Prof Li, from the Neural Stem Cells Laboratory at NNI, added, «This important study suggests a link between a key neurological disease gene and regulation of microRNAs in the brain.

In fact, so much of the progress that we're making in laboratories, including mine, is on developing neuroprotective therapies that can protect the retina from degeneration, regenerate optic nerve fibers all the way back to their targets in the brain, and even replace damaged retinal ganglion cells with self - therapies that completely rebuild the optic nervIn fact, so much of the progress that we're making in laboratories, including mine, is on developing neuroprotective therapies that can protect the retina from degeneration, regenerate optic nerve fibers all the way back to their targets in the brain, and even replace damaged retinal ganglion cells with self - therapies that completely rebuild the optic nervin laboratories, including mine, is on developing neuroprotective therapies that can protect the retina from degeneration, regenerate optic nerve fibers all the way back to their targets in the brain, and even replace damaged retinal ganglion cells with self - therapies that completely rebuild the optic nervin the brain, and even replace damaged retinal ganglion cells with self - therapies that completely rebuild the optic nerve.

He also studies brain cancer at the basic cell level in the Castro laboratory.

Current projects in the laboratory include: 1) functional screens of ubiquitin ligases to identify novel cancer drug targets; 2) defining the molecular regulation of breast cancer metastasis to the brain; and 3) understanding signaling pathways that influence the response of cancer cells to chemotherapy.

We have learned a fair amount from the neurologic genetic diseases, but we and others also studied these cells in the laboratory as well as in animal models of brain injury.

Previously, researchers in the laboratory of Gladstone Investigator Anatol Kreitzer, PhD, discovered how an imbalance in the activity of a specific category of brain cells is linked to Parkinson's.

Today, researchers in the laboratory of Gladstone Senior Investigator Lennart Mucke, MD, report in Nature Neuroscience that DSBs in neuronal cells in the brain can also be part of normal brain functions such as learning — as long as the DSBs are tightly controlled and repaired in good time.

By mimicking a molecular switch that triggers cell death, researchers have killed cells grown in the laboratory from one of the most resilient and aggressive cancers - a virulent brain cancer known...

The scientists said they created their mice from the brain cells of rodents that had been kept in laboratory conditions at -20 C.

In laboratory experiments the researchers mimicked the way SOX9 is stabilized in brain tumor cells and showed how SOX9 turned on 40 to 50 genes in the tumor to make it more resistant to chemotherapy and more prone to spreaIn laboratory experiments the researchers mimicked the way SOX9 is stabilized in brain tumor cells and showed how SOX9 turned on 40 to 50 genes in the tumor to make it more resistant to chemotherapy and more prone to spreain brain tumor cells and showed how SOX9 turned on 40 to 50 genes in the tumor to make it more resistant to chemotherapy and more prone to spreain the tumor to make it more resistant to chemotherapy and more prone to spread.

Dr. Kim's Molecular Neurobiology Laboratory, founded in 1998, studies the biology of brain cells that rely on the brain chemical dopamine to communicate.

Fortunately, emerging technology has made it possible to create brain, heart, and liver cells from a primate skin biopsy16 and edit the DNA of these cells in the laboratory.

The pattern of RGC loss in patients as well as information obtained from laboratory research all point to the fact that an important site of pathology occurs at the optic nerve head, a region where the axonal cell processes of RGCs exit the eye on their way to the visual centers of the brain.

Xiaoning Han and colleagues in the laboratories of Steven Goldman and Maiken Nedergaard at the University of Rochester Medical Center posed an interesting question — can you enhance the processing ability of one species by surgically implanting and grafting cells from the brain of another «smarter» species?

Gross brain pathology from infants with presumed or laboratory - confirmed ZIKV infection, primarily from neuroimaging, closely resembles neuropathology associated with congenital cytomegalovirus (CMV).48 The most notable difference is the distribution of intracranial calcifications (ie, typically subcortical in congenital ZIKV infection and periventricular in CMV).48, 49 Such calcifications are likely dystrophic and related to cell death, either by necrosis, apoptosis, or both.50

Supported by a CIRM translational grant, scientists in Huang's laboratory are using human stem cells to create inhibitory neuron progenitors — early - stage brain cells that can develop into mature inhibitory neurons.

The work in humans is complemented by laboratory work involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and animal models of deep brain stimulation.

In a laboratory study published in 2012 in Oncology Reports, chokeberries caused the death of malignant brain tumor cellIn a laboratory study published in 2012 in Oncology Reports, chokeberries caused the death of malignant brain tumor cellin 2012 in Oncology Reports, chokeberries caused the death of malignant brain tumor cellin Oncology Reports, chokeberries caused the death of malignant brain tumor cells.

Working in the dim light of an abandoned laboratory, a trainee technician with trembling hands embeds the DNA of a captured alien inside the nucleus of a cell extracted from the professor's own brain, and the first of a squadron of Square Avengers is spawned.

Alternating imagery of gravity - defying hummingbirds with footage shot in the Arctic and in laboratories where human brain cells are preserved in freezers for neurological research, Biggs paints a tender picture of life caught between hope and futility.