Not exact matches
The
chemicals in both bind to the mu opioid
receptor in the
brain.
Cannabinoids are why we're here: They're
chemical compounds that act on
receptors in the
brain and can alter neural function.
«There are
receptors in the
brain for melatonin that regulate
brain chemicals related to anxiety and calming,» he explains.
Using a small amount of a radioactive substance as a tracer, the scientists focused on the
brain's mu - opioid system in which
chemicals called endogenous opioids bind to
receptors and hinder the spread of pain messages in the
brain.
He works by tweaking the
chemical structures of the drugs, sometimes changing just a few molecules to see what impact this might have on the interaction between the drug and the
brain receptors their parent compounds normally act upon.
What's more, the gene codes for a
chemical receptor involved in many
brain functions, such as learning and memory, so the gene might also be involved in behavioral disorders.
One of your biggest discoveries was how addiction affects the D2
receptor, the protein that determines how sensitive individuals are to the release of the neurotransmitter dopamine, a
chemical in the
brain associated with feelings of reward and pleasure.
The scientists observed that transmission of
chemical signals between the nerve cells are facilitated by AMPA -
receptors and the activity occurs on the
brain cell surface.
In October researchers in Canada found that the depressed who commit suicide have an abnormal distribution of
receptors for the
chemical GABA, one of the most abundant neurotransmitters in the
brain.
Anandamide is among a class of naturally occurring
chemicals in the body known as endocannabinoids that attach to the same
brain cell
receptors as does marijuana's active ingredient, THC, with similar outcomes.
«The
brain along with the reproductive system and every other cell in your body is exquisitely sensitive to exceedingly small changes in estrogen and other sex hormones, and the fact that the environment is full of
chemicals that can activate estrogen
receptors means this phenomenally sensitive system is being perturbed constantly by environmental factors.»
«New drug could be safer, non-addictive alternative to morphine: The peptide - based drugs, which mimic a natural
brain chemical, target the same pain - relieving opioid
receptor as morphine.»
In a final experiment, when the researchers gave the bees a drug that disrupted
receptors for dopamine, a neurotransmitter linked with motivation and reward, the bias disappeared, echoing the way this
brain chemical works in mammals.
They traced the effect to changes in dopamine, a
brain chemical that contributes to the experience of reward, and to possible changes in GABA
receptors, which can act as a brake system to keep dopamine in check.
Receptors facilitate
chemical and electrical signals between neurons in the
brain, allowing those neurons to communicate with each other.
The drug boosted dopamine, a
brain chemical involved in pleasure and motivation, equivalently, but pair - bonded voles had fewer
receptors ready to receive the dopamine signal.
He examines several well - studied
receptors — the bacterial aspartate
receptor (Tar), human epidermal growth factor
receptor (EGFR), and human
brain - derived neurotrophin
receptor (BDNFR)-- and comes to a conclusion that they all have similar
chemical structures with or without their corresponding ligands.
The researchers looked in rats»
brains for the genetic instructions needed to make a key «pleasure
receptor,» called D2, that allows
brain cells to receive signals sent by the
brain chemical dopamine — or cocaine.
Instead, it acts on
chemicals in the
brain, primarily
receptors for serotonin, a
chemical messenger involved in mood, among many other things.
But it's the mu
receptor that is primarily responsible for opioids» analgesic effects, and drugs that fit it snugly launch a cascade of
chemical changes in nerve cells that slow down the transmission of pain messages to the spinal cord and the
brain.
Drugs used to treat
brain disorders often interact with
brain chemicals called neurotransmitters or the cell
receptors that interact with neurotransmitters.
These drugs are Dopamine agonists because they bind to the dopamine
receptors, and help with dopamine - mediated functions (dopamine being one of the
chemicals that is severely in the Parkinsonian
brain).
When certain
chemicals in food or other materials trigger a response in these
receptors, the
brain detects one or more flavors — sweet, sour, salty, bitter or umami.
When injected, the
chemical appears to kill off nerve endings and
receptors that are responsible for sending pain signals to the
brain.
Naturopathic physician, acupuncturist, and president of the New York Naturopathic Physicians, Peter Bongiorno, ND, explains that the thyroid affects every cell in the body, including the
brain receptors for serotonin — a
brain chemical that affects sleep.
A deficiency in serotonin causes depression and in some anxiety — in fact, the majority of antidepressants work by blocking the
brain's serotonin
receptors, freeing up more of the
chemical to remain present in the
brain.
«Psilocybin targets the serotonin
receptors in the
brain,» he said, «just as most antidepressants do, but it has a very different
chemical structure to currently available antidepressants and acts faster than traditional antidepressants.»
If your
brain can't generate and transmit the
chemicals that make you feel good, you'll seek the effects from outside sources, and food / booze / drugs plug up the same
receptors in the
brain as the neurotransmitters should.
These
chemicals cross the blood -
brain barrier, enter the
brain and bind to the same
receptors that bind opiates like morphine and heroin, triggering a mild euphoria.
These behavioral changes were associated with alterations in the GABA system of the
brain in the probiotic group, matching the known effects of antidepressant or anxiolytic
chemical agents (for example, anxiolytic agents such as benzodiazepines work at GABA
receptors)[91].
The
brain and the nervous system influence the skin's immune cells through various
receptors and
chemical messengers, and scientists are now investigating how these respond to psychological stress.
«By directly interacting with melatonin
receptors in the
brain and peripheral tissues, environmental
chemicals, such as carbaryl, may disrupt key physiological processes leading to misaligned circadian rhythms, sleep patterns, and altered metabolic functions increasing the risk for chronic diseases such as diabetes and metabolic disorders,» said Dubocovich.
«The effects of THC are felt when that
chemical makes its way to those
receptors within the
brain, according to Pedersen.
The mechanism of action is not exactly known, however, its thought to block
receptors of dopamine in the
brain, a
chemical used for cell - to - cell communication.