"Brain circuitry" refers to the intricate network of connections between different parts of the brain. It is like a complex road system, allowing information to travel and be processed, influencing our thoughts, actions, and emotions.
Full definition
Conversely, experiences that produce maladaptive changes
in brain circuitry underlie many neuropsychiatric disorders, and age - related decreases in brain plasticity contribute to age - related memory disorders such as Alzheimer's disease.
While lapses in attention preceded response inhibition errors in the children without ADHD,
brain circuitry involved in response selection and control was activated prior to errors in the children with ADHD.
Finding a neural substrate for social learning provides a different perspective into social behavior, with possible relevance to disorders such as autism, which are thought to involve abnormalities in the
same brain circuitry studied in this work.
Their goal is to better understand how this brain region regulates emotion, which, in turn, could lead to a greater understanding of
how brain circuitry is disrupted in depression, anxiety, PTSD, and other psychiatric conditions.
In the laboratory «Neural Basis of Sensorimotor Control» we
study brain circuitry mechanisms for voluntary movement control and sensory processing that involves the arm and hand.
Imaging various sections of white matter from different angles can help researchers focus on the underlying
brain circuitry important for proper neuron communication.
PULLMAN, Wash. — A WSU research team for the first time has developed a computer algorithm that is nearly as accurate as people are at mapping brain neural networks — a breakthrough that could speed up the image analysis that researchers use to
understand brain circuitry.
Using a molecular method likely to become widely adopted by the field, researchers supported by the National Institutes of Health have
discovered brain circuitry essential for alertness, or vigilance — and for brain states more generally.
The 2 - Year Window Mother Jones, November 18, 2011» «The concept of
disrupting brain circuitry is much more compelling than the concept that poverty is bad for your health,» says Professor Jack Shonkoff, a Harvard pediatrician and chair of the National Scientific Council on the Developing Child.
«The microchip technology also allows us to extract signals from the brain in order to reverse -
engineer brain circuitry and decode the information that is in the subject's mind.
The researchers were able to zero in on the Broca's area as well as
related brain circuitry specifically linked to speech, using regional cerebral blood flow as a measure of brain activity, since blood flow is typically coupled with neural activity.
Using a molecular method likely to become widely adopted by the field, researchers have discovered
brain circuitry essential for alertness — and for brain states more generally.
The slow and gradual addition of new nerve cells may be like a fine - tuning system, allowing adults to incorporate fresh information without altering our
basic brain circuitry.
«By discovering how the removal of RGS4
affects brain circuitry at the molecular level, we gained a deeper understanding of the protein's role — both normally and in Parkinson's disease,» said Dr. Lerner.
For example, scientists could confirm or disprove whether an experience was truly linked with specific
brain circuitry by first identifying networks activated when a rat encounters, say, an anxiety - provoking event, and afterwards stimulating that same network directly to determine whether the animal shows evidence of experiencing the same mental state.
It's because the distance between synapses carrying similar messages — positive or negative — shortens to make it easier for information to be shared
via brain circuitry.
Throw a bear hug into the mix — and the accompanying flood of oxytocin — and that
old brain circuitry lit up like fireworks.
Hormones drive many of these sex differences, while major life events — such as puberty, pregnancy, parenthood or even traumas — also help shape male and
female brain circuitry.
«This is one of the first studies providing clear evidence showing that
different brain circuitry is involved in different types of depressive behavior with specific symptoms,» said Lim.
The idea that
brain circuitries devoted to affiliation and social bonds may well be as sophisticated as our fear mechanisms had been percolating for almost a decade.
«It is exciting to find a correlation
between brain circuitry and gene expression by combining high quality data from these two large - scale projects,» says David Van Essen, Ph.D., professor at Washington University in St. Louis and a leader of the Human Connectome Project.
One framed artwork, however, connects Shatz to her childhood, and the earliest influences on her
own brain circuitry.
This
aberrant brain circuitry — the amyloid plaques and tau tangles — became the twin hallmarks of the disease that bears his name.
«This discovery not only will lead to new insight into how
brain circuitry develops but to new insight into declining brain function that occurs with aging.»
Looking further, Deligiannidis has also examined the role of certain steroids synthesized from progesterone and other hormones and known to affect
maternal brain circuitry.
The authors of the study said the key question moving forward is to understand what specific changes in
brain circuitry give rise to the effects observed in this study.
If lamprey software can help people with spinal injuries, it will be in the shape of
animal brain circuitry realised on a chip wired into a human being — a kind of cyborg sandwich.
Karl Deisseroth, an optogenetics pioneer at Stanford University, has used the technique with animals to learn more about the nature of the
disordered brain circuitry in Parkinson's.
«Our goal in the project was to close the gap in knowledge that exists on role of serotonin in the brain cortex, particularly as it
concerns brain circuitry, its electrical activity and function,» said Roberto Fernández Galán, PhD, Assistant Professor in the Department of Neurosciences at Case Western Reserve University School of Medicine.
The
abnormal brain circuitry of LKS patients renders the brain incapable of imprinting memory, further impairing brain function.
Although the details are murky, bad language seems to hinge on evolutionarily
ancient brain circuitry with intimate ties to structures that process emotions.
We hope that our work will provide new insight into the signaling mechanisms responsible for
establishing brain circuitry, and ultimately suggest therapeutic interventions for disorders in which these signaling mechanisms are perturbed.
«Once we start to correlate particular patterns of activity to behaviors or mental states,» says Rafael Yuste, a neuroscientist at Columbia University who studies
mammalian brain circuitry, «we will reinvent neuroscience as a field.»
Sawchenko's lab also aims to
unravel brain circuitry related to past experience, emotion and stress in the hopes of better understanding a range of psychiatric disorders, including depression and post-traumatic stress disorder (PTSD).
14C -2-deoxyglucose autoradiography screen for mouse brain activity: relating known therapeutics and novel compounds for schizophrenia, depression, and bipolar disorder to
brain circuitry A. GIOVANNI, S. ENGEL, C. BOWEN, R. TERRY - LORENZO, P. G. JONES, L. HARDY, T. LARGE, T. HANANIA, E. V. SABATH, V. ALEXANDROV, M. QUTAISH, M. SEAMAN, P. CZARNECKI, M. SILVA, J. SULLIVAN... Abstract > / Posters
Unlike earlier animal models of central nervous system disorders that have emphasized trying to re-create behaviors that «look like» the diseases in humans, Feng aims to model the
dysfunctional brain circuitry that underlies the behaviors.
In functional neurology, we examine brain function through various tests that evaluate reflexes, movement and balance, responses to stimuli, and how the eyes move — the eyes are a window into how
well brain circuitry functions.