No laughing matter: Intranasal oxytocin administration changes functional
brain connectivity during exposure to infant laughter
Since the initial fMRI reports of hypo - connectivity in autism (Just et al., 2004), task - related reductions in inter-regional
brain connectivity during language (Just et al., 2004; Mason et al., 2008; Jones et al., 2010), working memory (Koshino et al., 2005, 2008), mental imagery (Kana et al., 2006), executive functions (Just et al., 2007), cognitive control (Kana et al., 2007; Solomon et al., 2009; Agam et al., 2010), visuomotor coordination (Villalobos et al., 2005) and social cognition (Kleinhans et al., 2008; Kana et al., 2009) have been documented.
Not exact matches
Researchers specifically analyzed how different areas of the
brain activate in sync with each other — a property called functional
connectivity —
during a period of rest.
Using two data sets of functional MRI
brain scans from more than 350 adult and child siblings
during resting state, Fair and colleagues applied an innovative technique to characterize functional
connectivity and machine learning to successfully identify siblings based on their connectotype.
The researchers were attempting to look at the
brain's so - called «functional
connectivity,» that is, interactions between
brain regions
during the course of a particular task, or at rest, Laird said.
In this study, the researchers aimed to investigate task related
brain activity and functional
connectivity patterns following onset of a regional anesthetic nerve block
during continuous noxious dental stimulation.
«Once we unravel the different working patterns and circuits in the
brain during memory formation and decision - making, we can begin to look for differences in
connectivity patterns that underlie abnormalities,» Harvey said.
They also found that the disruption of the
connectivity of these cells
during brain development causes alterations in
brain oscillatory activity and disturbs the function of place cells, a type of pyramidal neuron that becomes active when an animal is located in a particular place in its environment.
Our data reflects the level of efficient organization of the functional
brain network
during a resting state and not the efficiency of functional
connectivity between
brain regions
during the performance of specific cognitive tasks that enter into the IQ score.
Dr. Elias and the OCAR primarily focus on understanding why ERP works (e.g., fear tolerance versus fear habituation; the roles of guilt, willingness, and acceptance; patterns of
brain activation
during exposure; functional
connectivity among
brain regions), tailoring treatment to the individual (e.g., elucidation of predictors of response and their underlying processes / mechanisms and neural correlates; rigorous diagnostic characterization of obsessive compulsive related disorders), and evaluating innovative treatments and augmentation strategies (e.g., acceptance and commitment therapy; optimization of inhibitory learning; pharmacological augmentation).
Task - based functional
connectivity measures the synchronization of activation levels between
brain regions
during the performance of a given cognitive task.
Previous studies of resting state functional
connectivity have demonstrated that the default - mode network (DMN) is negatively correlated with a set of
brain regions commonly activated
during goal - directed tasks.
Resting - state functional magnetic resonance imaging allows investigating whole -
brain connectivity changes
during pharmacological modulation of the level of consciousness.Low - frequency spontaneous blood oxygen level - dependent fluctuations were measured in 19 healthy volunteers
during wakefulness, mild sedation, deep sedation with clinical unconsciousness, and subsequent recovery of consciousness.Propofol - induced decrease in consciousness linearly correlates with decreased corticocortical and thalamocortical
connectivity in frontoparietal networks (i.e., default - and executive - control networks).
«In general, the additional
brain size and
connectivity of the human
brain compared to the chimpanzee or macaque, along with the protracted period of time
during which human neurodevelopment occurs, means that there are many more problems than can arise and a greater period of time
during which those problems can occur,» Sestan explained.
â $ œOur findings fit into an emerging theme in neuroscience research: that
during childhood, there is a switch in amygdala function and
connectivity with other
brain regions, particularly the prefrontal cortex, â $ says Mar Sanchez, PhD, neuroscience researcher at Yerkes and associate professor of psychiatry and behavioral sciences at Emory University School of Medicine.
During the resting
brain scan, the treatment group also showed greater
connectivity between a region known as the «periaqueductal grey» and areas of the prefrontal cortex associated with cognition.
And studies using functional MRI measures have shown that the amount of cortical
brain area used is greater
during eccentric contractions than in concentric contractions (Yao et al. 2014), while functional
connectivity between the primary motor cortex and other parts of the
brain is reduced (Yao et al. 2016).
This week, I'm covering «Associations Between SSRI Exposure
During Pregnancy and MRI - Assessed
Brain Structure and
Connectivity in Infants»:
Childhood Maltreatment Is Associated With Altered Fear Circuitry and Increased Internalizing Symptoms by Late Adolescence (PDF - 686 KB) Herringa, Birn, Ruttle, Burghy, Stodola, Davidson, & Essex (2013) Proceedings of the National Academy of Sciences of the United States of America, 110 (47) Examines the associations between experiences of maltreatment
during childhood and functional
brain connectivity in 64 adolescents participating in a longitudinal community study.