In the case of planarians, the gene egr - 4 seems to perform an early control of cell proliferation as a response to amputation, and be involved later in the early differentiation of brain during regeneration.
Since 2011, as an associate professor at Stanford University, I have led a team focused on synaptic changes occurring during normal and pathological behaviors (sleep, fragile X syndrome, ASD) as well as eye / brain neuronal regeneration.