Sentences with phrase «brain dysfunction in»

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Without those nerve endings and the feedback to the brain, circumcised men suffer premature ejaculation (the # 1 sexual complaint of circumcised American men) and later in life sexual dysfunction and impotence.

In fact, for many years ADHD was called «minimal brain damage» or «minimal brain dysfunction.»

He said the abuse of Tramadol could result in erectile dysfunction, infertility, brain damage among others.

The latter substance, phosphorylated tau, is responsible for neurofibrillary tangles, which are suspected of contributing to the nerve cell dysfunction in the brain that is responsible for Alzheimer's memory symptoms.

«As a dysfunction in the ability of the brain to regulate the communication of information between brain regions,» Khambhati said, «seizures can be thought of as a traffic flow problem.

In an earlier study published in Nature Medicine, an international team of scientists discovered that the additional copy of chromosome 21 in Down's syndrome reduces the production of SNX27 in the brain and results in synaptic dysfunctioIn an earlier study published in Nature Medicine, an international team of scientists discovered that the additional copy of chromosome 21 in Down's syndrome reduces the production of SNX27 in the brain and results in synaptic dysfunctioin Nature Medicine, an international team of scientists discovered that the additional copy of chromosome 21 in Down's syndrome reduces the production of SNX27 in the brain and results in synaptic dysfunctioin Down's syndrome reduces the production of SNX27 in the brain and results in synaptic dysfunctioin the brain and results in synaptic dysfunctioin synaptic dysfunction.

Chemically intolerant individuals also show dysfunction in brain imaging on a SPECT scan, which tracks blood flow through tissue.

«We now have a handle on the detailed structure of a complex web of interactions that causes global dysfunction in cells resulting in degeneration of the brain.»

«While dopamine has limited reach in the brain, any dysfunction in glutamate would be expected to have the sort of widespread effects we see in the perceptual disorders associated with schizophrenia,» says Albright.

Similar types of more severe cognitive dysfunction are common in brain cancer patients who have received high - dose, photon - based radiation treatments.

«The role of IL - 2 in delirium is a new finding and is particularly interesting since it was reported to induce blood - brain barrier dysfunction in animal models,» she added.

The circuit incorporates brain regions involved in reward and pleasure, leading the authors to consider that social dysfunction may stem from reduced enjoyment in social interaction.

This suggests that TBI may trigger a vicious cycle, in which brain injury causes gut dysfunction, which then has the potential to worsen the original brain injury.

Professor Kieran Murphy, Head of Department of Psychiatry, RCSI and Consultant Psychiatrist at Beaumont Hospital, said: «We have shown for the first time that dysfunction of the blood - brain barrier may be an important factor in the development of schizophrenia.

This new study builds on previous research from this group showing that elevated blood levels of SNTF on the day of a mild traumatic brain injury treated in the emergency room predicted those patients who would go on to suffer diffuse axonal injury and long - term cognitive dysfunction.

The findings, published in the Nov. 19 Journal of Neuroscience, could shift researchers» attention from the spinal cord to the brain's motor cortex as the disease's initial point of dysfunction.

The differences in fear sensitivity are likely to be innate, at least in part: dysfunction in the amygdala, a brain area important for processing fear, has previously been linked to psychopathic behaviour, and genetic factors must underlie some of these differences.

«The imaging technique could shed light on the immune dysfunction that underpins a broad range of neuroinflammatory diseases, such as Alzheimer's disease, depression, post-traumatic stress disorder and addiction,» said Christine Sandiego, PhD, lead author of the study and a researcher from the department of psychiatry at the Yale School of Medicine in New Haven, Conn. «This is the first human study that accurately measures this immune response in the brain.

«We have shown that just six weeks in an enriched environment can help animals recover from cognitive dysfunctions after traumatic brain injury,» said Prof. Pick.

Concussions that lead to lasting brain dysfunction cause SNTF to accumulate in vulnerable long axon tracts of the brain, and its blood elevation is a measure of this diffuse axonal injury.

Dysfunction in dopamine signaling profoundly changes the activity level of about 2,000 genes in the brain's prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, according to UC Irvine scientists.

This kind of progressive speech impairment is associated with dysfunction in the cortical - basal ganglia brain circuit in both humans and songbirds, so Liu could make assumptions based on this trial about how the human brain circuit changes.

Developing such biomarkers to assess brain dysfunction will be a challenge, but in the same issue you draw attention to the excellent work of Abdul Hye and his colleagues who are developing a test to detect protein biomarkers for Alzheimer's disease in blood (p 5).

«A dysfunction in the brain messenger dopamine is common to both Parkinson's and RLS, and has been hypothesized as a possible cause of migraine for many years.

«Repetitive blast exposure causes cerebellar dysfunction in combat veterans: Researchers help bridge knowledge gap in brain injuries.»

Huntington's disease, for example, is caused by aggregating proteins inside brain neurons that ultimately lead to motor dysfunction, personality changes, depression and dementia, usually progressing rapidly after onset in people's 40s.

Using this imaging technology, we may be able to capture more precise and objective measurements of olfactory dysfunction and better understand how changes in these sensory neurons relate to overall health and neurodegeneration in the brain.»

Published in Nature Neuroscience, the findings suggest that astrocytes — star - shaped cells that are abundant in the brain and support neuronal function — are important regulators of information storage, and their dysfunction might lead to memory decline in disease.

It is also suggested that further elucidation of the mechanism linking mastication and brain function can lead to novel treatments and preventive measures for memory / learning dysfunction in the future.

The grand symphonic piece that is consciousness encompasses the foundational contributions of the brain stem, forever hitched to the body, and the wider - than - the - sky imagery created in the cooperation of cerebral cortex and subcortical structures, all harmoniously stitched together, in ceaseless forward motion, interruptible only by sleep, anesthesia, brain dysfunction, or death.

Researchers with Oregon Health & Science University's Vollum Institute have given science a new and unprecedented 3 - D view of one of the most important receptors in the brain — a receptor that allows us to learn and remember, and whose dysfunction is involved in a wide range of neurological diseases and conditions, including Alzheimer's, Parkinson's, schizophrenia and depression.

In particular, obesity has been linked with dysfunction of the hippocampus, an area of the brain involved in memory and learning, and of the frontal lobe, the part of the brain involved in decision making, problem solving and emotions, suggesting that it might also affect memory; however, evidence for memory impairment in obesity is currently limiteIn particular, obesity has been linked with dysfunction of the hippocampus, an area of the brain involved in memory and learning, and of the frontal lobe, the part of the brain involved in decision making, problem solving and emotions, suggesting that it might also affect memory; however, evidence for memory impairment in obesity is currently limitein memory and learning, and of the frontal lobe, the part of the brain involved in decision making, problem solving and emotions, suggesting that it might also affect memory; however, evidence for memory impairment in obesity is currently limitein decision making, problem solving and emotions, suggesting that it might also affect memory; however, evidence for memory impairment in obesity is currently limitein obesity is currently limited.

For example, how genetic programs affect the function of specific cell types, how they vary early or later in life and how dysfunction in these programs might contribute to disease, all of which could help scientists learn more about the fundamental workings of the brain.

Every year, nearly two million people in the United States suffer traumatic brain injury (TBI), the leading cause of brain damage and permanent disabilities that include motor dysfunction, psychological disorders, and memory loss.

With the former it is possible that something similar genetically underlies both ADHD and obesity; Castellanos and his colleagues note that dysfunction in the dopamine pathways of the brain have been found among both people who are obese and those with ADHD.

In humans, the cerebellum's extensive connectivity with the rest of the brain suggests it does far more than learn motor skills: it has been shown to have a part in both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as schizophrenia and autisIn humans, the cerebellum's extensive connectivity with the rest of the brain suggests it does far more than learn motor skills: it has been shown to have a part in both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as schizophrenia and autisin both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as schizophrenia and autism.

The volume of gray matter is a measure of brain health, but the amount of gray matter in the brain often begins to decrease in late adulthood, even before symptoms of cognitive dysfunction appear.

Damage to astrocytes — star - shaped cells found in the brain and spinal cord — is found in many neurodegenerative conditions, but it's been unclear exactly what role astrocyte dysfunction plays in the development of disease.

In contrast to targeting genetic sources of dysfunction, Levin believes electrical manipulation could serve as a larger - level and more efficient control dial for brain development.

Moreover, the brain's two dozen or so connector hubs play a key role in complex cognitive tasks, and are vulnerable to brain damage and dysfunction.

In soldiers who survive traumatic brain injury from blast exposure, pituitary dysfunction after their blast injury may be an important, under - recognized, and potentially treatable source of their symptoms, a new study finds.

In doing so, they may have left our brains prone to occasional complex dysfunction — but also capable of biomedical research aimed at one day curing the ailing brain.

«And many studies of the brain and central nervous system, using imaging, EEG and other objective measures of brain structure and function, add to the existing evidence that central nervous system dysfunction is a critical element in the disorder.

The ultimate goal is to better understand how the billions of neurons in the brain communicate with one another during normal brain function, or dysfunction, as result of injury or disease.

Like humans with AD, hAPP mice have elevated levels of amyloid β (Aβ) peptides in the brain, network and synaptic dysfunction, and amyloid plaques (9).

Research Interests: Clinical pharmacology of anticancer agents; early phase drug development; drug tolerability in cancer patients with HIV / AIDS; drug tolerability in cancer patients with organ dysfunction; blood - brain barrier penetration of drugs.

We aim to identify molecular, circuit, and network mechanisms of cognitive dysfunction and to develop novel therapeutic approaches to restore brain functions in AD and related disorders.

The more we understand about how natural variation in the vertebrate genome shapes the development and function of the brain, the better insight we can have into how behavioral patterns evolve, and how disruption to neurogenetic pathways can lead to brain and behavioral dysfunction.

Recent large - scale efforts have launched a new generation of studies that aim to identify the molecular and cellular characteristics of the brain and how these translate into normal brain function — or, in the case of disease, dysfunction.

His research interests include cognitive dysfunction in aging, dementia, and Alzheimer Disease, concussion recovery, neuropsychiatric syndromes, and traumatic brain injury.